文章摘要
仇元营,王松强,王小丽,卢伟霞,乔丹,李建彬,谷园园,曾艳,陈滢,白伟志,许汴利,韩同武.一起新型冠状病毒肺炎家庭聚集性流行病学分析[J].中华流行病学杂志,,():494-497
一起新型冠状病毒肺炎家庭聚集性流行病学分析
Epidemiological analysis on a family cluster of COVID-19
收稿日期:2020-02-21  出版日期:2020-03-05
DOI:10.3760/cma.j.cn112338-20200221-00147
中文关键词: 新型冠状病毒肺炎;家庭聚集性;流行病学分析
英文关键词: COVID-19;Family cluster;Epidemiological analysis
基金项目:
作者单位E-mail
仇元营 郑州市疾病预防控制中心 450007  
王松强 郑州市疾病预防控制中心 450007  
王小丽 郑州市疾病预防控制中心 450007  
卢伟霞 郑州市疾病预防控制中心 450007  
乔丹 郑州市疾病预防控制中心 450007  
李建彬 郑州市疾病预防控制中心 450007  
谷园园 郑州市金水区疾病预防控制中心 450000  
曾艳 郑州市金水区疾病预防控制中心 450000  
陈滢 郑州市金水区疾病预防控制中心 450000  
白伟志 郑州市金水区疾病预防控制中心 450000  
许汴利 河南省疾病预防控制中心, 郑州 450016 bianlixu@163.com 
韩同武 郑州市疾病预防控制中心 450007 tongwuhan@126.com 
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中文摘要:
      目的 针对郑州市一起新型冠状病毒肺炎(COVID-19)家庭聚集性疫情进行流行病学调查分析,探讨可能的传播模式和潜伏期传染性,为及时控制传染源、遏制疫情扩散提供科学依据。方法 采用描述性流行病学方法对8例病例进行流行病学调查分析,通过实时荧光定量PCR方法对采集的呼吸道标本进行2019-nCoV核酸检测。结果 2例具有共同武汉暴露史的病例,分别于1月31日、2月1日发病;其他6位家庭成员中1例于1月30日发病,1例于1月31日发病,3例于2月1日发病、1例于2月3日发病。结论 此次COVID-19家庭聚集性疫情,2例原发病例通过家庭共同暴露传染给其余6位家庭成员,5例续发病例发病日期早于或与原发病例同日发病,提示潜伏期具有传染性,早期居家隔离措施可能导致家庭聚集疫情风险。
英文摘要:
      Objective To understand the possible transmission route of a family cluster of COVID-19 in Zhengzhou and the potential infectivity of COVID-19 in incubation period, and provide scientific evidence for the timely control of infectious source and curb the spread of the epidemic. Methods Epidemiological investigation was conducted for a family cluster of COVID-19 (8 cases) with descriptive epidemiological method, and respiratory tract samples of the cases were collected for the nucleic acid detection of 2019-nCoV by RT-PCR. Results Two primary cases, which occurred on 31 January and 1 February, 2020, respectively, had a common exposure history in Wuhan. The other six family members had onsets on 30 January, 31 January, 1 February (three cases) and 3 February, 2020. Conclusions In this family cluster of COVID-19, six family members were infected through common family exposure to the 2 primary cases. Five secondary cases had onsets earlier than or on the same day as the primary cases, indicating that COVID-19 is contagious in incubation period, and the home isolation in the early phase of the epidemic might lead to the risk of family cluster of COVID-19.
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