| 仇元营,王松强,王小丽,卢伟霞,乔丹,李建彬,谷园园,曾艳,陈滢,白伟志,许汴利,韩同武.一起新型冠状病毒肺炎家庭聚集性流行病学分析[J].中华流行病学杂志,,():494-497 |
| 一起新型冠状病毒肺炎家庭聚集性流行病学分析 |
| Epidemiological analysis on a family cluster of COVID-19 |
| 收稿日期:2020-02-21 出版日期:2020-03-05 |
| DOI：10.3760/cma.j.cn112338-20200221-00147 |
| 中文关键词: 新型冠状病毒肺炎;家庭聚集性;流行病学分析 |
| 英文关键词: COVID-19;Family cluster;Epidemiological analysis |
| 基金项目: |
| 作者 | 单位 | E-mail | | 仇元营 | 郑州市疾病预防控制中心 450007 | | | 王松强 | 郑州市疾病预防控制中心 450007 | | | 王小丽 | 郑州市疾病预防控制中心 450007 | | | 卢伟霞 | 郑州市疾病预防控制中心 450007 | | | 乔丹 | 郑州市疾病预防控制中心 450007 | | | 李建彬 | 郑州市疾病预防控制中心 450007 | | | 谷园园 | 郑州市金水区疾病预防控制中心 450000 | | | 曾艳 | 郑州市金水区疾病预防控制中心 450000 | | | 陈滢 | 郑州市金水区疾病预防控制中心 450000 | | | 白伟志 | 郑州市金水区疾病预防控制中心 450000 | | | 许汴利 | 河南省疾病预防控制中心, 郑州 450016 | bianlixu@163.com | | 韩同武 | 郑州市疾病预防控制中心 450007 | tongwuhan@126.com |
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| 中文摘要: |
| 目的 针对郑州市一起新型冠状病毒肺炎（COVID-19）家庭聚集性疫情进行流行病学调查分析，探讨可能的传播模式和潜伏期传染性，为及时控制传染源、遏制疫情扩散提供科学依据。方法 采用描述性流行病学方法对8例病例进行流行病学调查分析，通过实时荧光定量PCR方法对采集的呼吸道标本进行2019-nCoV核酸检测。结果 2例具有共同武汉暴露史的病例，分别于1月31日、2月1日发病；其他6位家庭成员中1例于1月30日发病，1例于1月31日发病，3例于2月1日发病、1例于2月3日发病。结论 此次COVID-19家庭聚集性疫情，2例原发病例通过家庭共同暴露传染给其余6位家庭成员，5例续发病例发病日期早于或与原发病例同日发病，提示潜伏期具有传染性，早期居家隔离措施可能导致家庭聚集疫情风险。 |
| 英文摘要: |
| Objective To understand the possible transmission route of a family cluster of COVID-19 in Zhengzhou and the potential infectivity of COVID-19 in incubation period, and provide scientific evidence for the timely control of infectious source and curb the spread of the epidemic. Methods Epidemiological investigation was conducted for a family cluster of COVID-19 (8 cases) with descriptive epidemiological method, and respiratory tract samples of the cases were collected for the nucleic acid detection of 2019-nCoV by RT-PCR. Results Two primary cases, which occurred on 31 January and 1 February, 2020, respectively, had a common exposure history in Wuhan. The other six family members had onsets on 30 January, 31 January, 1 February (three cases) and 3 February, 2020. Conclusions In this family cluster of COVID-19, six family members were infected through common family exposure to the 2 primary cases. Five secondary cases had onsets earlier than or on the same day as the primary cases, indicating that COVID-19 is contagious in incubation period, and the home isolation in the early phase of the epidemic might lead to the risk of family cluster of COVID-19. |
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