文章摘要
冯崇慧.新疆出血热病毒抗原性的初步分析[J].中华流行病学杂志,1983,4(2):92-95
新疆出血热病毒抗原性的初步分析
Preliminary Study on Antigenicity of Xinjiang Hemorrhagic Fever Virus
收稿日期:  出版日期:2021-06-09
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冯崇慧 新疆自治区卫生防疫站 
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中文摘要:
      新疆出血热分布在塔里木河流域的广大地区,从各种不同临床类型的病人,不同地区的蜱、绵羊以及野生动物(大耳跳鼠)中分离到多株病毒。这些毒株在抗原性上有无差别是本病流行病学、病原学和免疫学上的一个有意义的问题。本文通过豚鼠交叉免疫攻击试验、交叉反向间接血抑试验、双向免疫扩散试验和恢复期病人血清对不同毒株抗原的补结和间接血抑试验等四种试验所得到的结果,初步表明这些毒株在抗原性上是一致的。
英文摘要:
      Xinjiang hemorrhagic fever spreads widely throughout the valley of Talimu River. Many strains of this virus have been isolated from patients with clinical various types, the ticks, shcep and wild emammals (Euchoreutes naso Sclater) from differnt localities in the affected area. It was thought that the homogenicity or heterogenicity of their antigens was closely linked to epidemiology, etiology and immunology of the disease. The author carried out immunity challenge test on guinea pigs, cross reverse indirect HAI test, double immanodiffussion test CFT and indirect HAI test with the sera of convalescents.The preliminary results indicated that these were homogenicity of the virus strains tested.
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