文章摘要
任铁生,许海修,龚惠心,周锦俊,昌云生,赖志辉.我国十县农村胃癌病例-对照调查研究[J].中华流行病学杂志,1985,6(1):29-32
我国十县农村胃癌病例-对照调查研究
A Case-Control Study on Gastric Cancer in ten rural Counties, China
收稿日期:  出版日期:2021-05-20
DOI:
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基金项目:
作者单位
任铁生 天津医学院 
许海修 山东医科院流研所 
龚惠心 西安医学院 
周锦俊 北京肿瘤防治研究所 
昌云生 山东省昌潍地区卫生局 
赖志辉 广东省韶关地区防疫站 
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中文摘要:
      我们于1978~1980年间在我国十个县,完成了686对病例-对照研究。本次调查发现胃癌与霉粮霉饭、饮食不规律,精神创伤及家族胃癌史等有关。有7个县霉粮霉饭因素相对危险性大于2,RRMH为2.06.精神创伤因素RR大于2.8的有7个县。饮食不规律因素RR ≥ 2的有5个县,RRMH为1.28(P<0.05)。病例组家族胃癌患病率为7.58‰,对照组家族胃癌患病率为4.02‰,前者显著高于后者(P<0.01)。调查发现新鲜蔬菜RRMH为0.88,说明它是保护因素之一。
英文摘要:
      A case-control study of 686 pairs was carried out in ten counties in China during 1978-1980.Among these pairs, the new diagnosed cases of gastric carcinoma and the health controls were 345 pairs,while the deceased cases of gastric cancer and non-cancer ous deceased control were 341 pairs.
It's found that gastric cancer is significantly related to mildewed foods, irregular time of meals, heavy psychic trauma, high-salt foods, smoking, drinking and family history of gastric cancer, etc.The relative risk (RR) of these factors is as follows:RR of the mildewed foods is over 2 in seven counties and combined relative risk (RRMH) is 2.06. RR of heavy psychic trauma is over 2.8 in seven counties. RR of irregular time of meals is over 2 (five counties) and RRMH is 1.28 (P<0.05). Prevalence rate of gastric cancer in the family is 7.58‰, in case-group and 4.02‰ in control group.The difference between the two groups is highly significant (P<0.01). Fresh vegetables (RRMH=0.88) play an important role in the prevention of gastric carcinoma.
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