文章摘要
王国栋,李世光,恒淑卿,刘隆健,杨文秀,张文峰,米尔英,赵习芳,刘玉萍,关丽华.一起由大白鼠引起的肾综合征出血热爆发的调查报告[J].中华流行病学杂志,1985,6(4):233-235
一起由大白鼠引起的肾综合征出血热爆发的调查报告
Survey of An Outbreak of Hemorrhagic Fever with Renal Syndrome As A Result of Experimental white Rat Infection
收稿日期:  出版日期:2021-05-22
DOI:
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作者单位
王国栋 山西医学院 
李世光 山西医学院 
恒淑卿 山西医学院 
刘隆健 山西医学院 
杨文秀 山西医学院 
张文峰 河北省邯郸地区防疫站 
米尔英 山西省卫生防疫站 
赵习芳 山西省卫生防疫站 
刘玉萍 山西省卫生防疫站 
关丽华 山西省卫生防疫站 
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中文摘要:
      1983年4~8月,某院实验室和动物室的工作人员中首次爆发了HFRS,发生病例16人,罹患率27%。其中教师6人,研究生2人,实验技术人员3人,实习生2人和动物饲养员3人。病人一般症状轻,无一例死亡。用间接荧光技术检查各室工作人员42人。其中有16例病人HFRS抗体全部阳性,而26名健康者中,有4人杭体阳性,提示隐性感染的存在。检查了126只大白鼠的肺,HFRS病毒抗原阳性21只,带毒率为16.7%。流行病学调查说明大白鼠为本次HFRS爆发的传染源。
英文摘要:
      There was an outbreak of hemorhagic fever with renal syndrome (HFRS) among the staff members in a laboratory and animal room of a college during April to August 1983. 16 out of 60 (27%) staff had HFRS and the disease appeared to be a mild but typical clinical course. The patients composed of 6 teachers, 2 postgraduate students, 3 technicians, 2 students of practice, and 3 animal raisers. The HFRS antibody was tested on 42 staff, who has worked in the laboratory and animal room, with indirect immunofluoresent technique. The results showed that the antibody titers were significantly raised in all 16 patients, and were positive in 4 out of other staff who had no HFRS. The HFRS antigen was detected in the lungs of 21 out of 126 rats (16.7%) with the immunofluorecentassay. The epidemiological study suggested that rats were the source of infection in this outbreak.
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