| 李贤凤,宋丽玉,李世清,潘亮,倪大石,周宁,何浩,李永珍.福建肾综合征出血热野鼠型和家鼠型病毒毒力差异的初步观察[J].中华流行病学杂志,1989,10(1):14-17 |
| 福建肾综合征出血热野鼠型和家鼠型病毒毒力差异的初步观察 |
| Preliminary Study on the Virulent Difference between Viral Strains Isolated from Rattus norvegicus and Apodemus agrarius in Fujian Province |
| 收稿日期: 出版日期:2021-06-02 |
| DOI： |
| 中文关键词: 肾综合征出血热 毒力 |
| 英文关键词: HFRSV Virulence |
| 基金项目: |
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| 中文摘要: |
| 肾综合征出血热褐家鼠型和黑线姬鼠型之间,除流行特征、临床症状及病毒抗原性方面有差异外,其病毒毒力亦有不同。非流行区家鼠型病毒株的毒力比流行区野鼠型的弱。乳小鼠可用于测定本病病毒株毒力。福建南部广泛存在出血热疫源地,但除个别地区偶发少数轻型病例外,多数地区为无病例区或隐性感染区,这是与该地区褐家鼠型病毒株毒力较弱有关。该病的流行与否及其强度,和当地是否存在有野鼠型病毒株有明显关系。 |
| 英文摘要: |
| Virulence between virus strains of hemorrhagic fever with renal syndrome(HFRS) from R. norvegicus and A.agrarius were different,besides the diversity in their epidemiological feature,clinical symptoms and antigenicity. Virulence of the virus strains from R.norvegicus, especially those from nonepidemic areas, were weak than those from A.agrarius.Sucking mice might be used for determining virulence of the virus strains from various source.Foci of HFRS had been in southern Fujian, but human cases of HFRS had rarely been found, or only a few mild cases were found in a few areas.This might be related to weaker virulence of the virus strains from R.norvegicus.The prevalent degree of the disease might be related to HFRSV of wild rattus type in the area. |
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