| 李会庆,许海修,李笠,金世宽,高雪芹,孙汭,袁新蓉,马庆恒.饮食与萎缩性胃炎的病例对照研究[J].中华流行病学杂志,1989,10(4):227-230 |
| 饮食与萎缩性胃炎的病例对照研究 |
| Atrophied Gastritis and Diet Case-control Study |
| 收稿日期: 出版日期:2021-06-01 |
| DOI： |
| 中文关键词: 萎缩性胃炎 病例对照 条件Logistic回归 |
| 英文关键词: Diet Atrophied gastritis Case-control Conditionai logistic regression |
| 基金项目: |
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| 摘要点击次数: 1935 |
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| 中文摘要: |
| 本文在山东省胃癌高发区对62例经组织学诊断的萎缩性胃炎按1:3配对,用条件Logistic回归模型进行了病例对照研究分析。评价指标为OR及95% CI分析结果表明,维生素B1对萎缩性胃炎有保护作用,达显著水平。而饮酒年数≥5年为萎缩性胃炎的危险因素。胡萝卜素、维生素C、缬氨酸摄入量高趋向为保护因素;吸烟年数≥5年和色氨酸摄入量高趋向为危险因素,但都未达显著水平,有待进一步研究验证。 |
| 英文摘要: |
We carried out a case-control study to explore the relationship between atrophied gastritis and diet in Yantai District of Shandong Province where stomach cancer incidence is very high. The cases were diagnosed by histology from Jan. 1983 to Dec. 1986 in three hospitals of Qixia, Laiyang, and Zhaoyuan counties. The controls were selected from local rural population. The method of sampling was first to select two communities, then according to household registration to select at random controls with matched sex and age (a difference of less than one year as compared with cases). The total number of cases and that of controls was 62 cases and 186 controls, respectively.
The data obtained by interviewers, who were trained before investigation, using a uniform questionaire including diet history of 1965. The quantities of eight essential amino acids and vitamin B1, B2, C, and carotene were calculated from food intake. All contineous variables were changed into order variables, then conditional logistic regression models were used to estimate adjusted OR (odds ratio) and its 95% CI (confidence interval).
The results showed that vitamin B1 exerted a protective effect for atrophied gastritis, and drinking alcohol was a risk factor. Carotene, vitamin C, and valine tended to be protective factors, but smoking and high tryptophane intake tended to be risk factors.However, all of them did not reach significant levels. |
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