文章摘要
陈重昇,俞莉,张汝黻,杨平.福建省莆田市黄石乡饮用水亚硝胺污染的调查[J].中华流行病学杂志,1989,10(6):359-362
福建省莆田市黄石乡饮用水亚硝胺污染的调查
Investigation on Nitrosamine in Drinking Water in Huang Shi——A High-risk Area of Stomach Cancer in Fujian Province
收稿日期:  出版日期:2021-06-03
DOI:
中文关键词: 饮用水  亚硝胺
英文关键词: Drinking water  Nitrosamine
基金项目:
作者单位
陈重昇 北京市肿瘤防治研究所 
俞莉 北京市肿瘤防治研究所 
张汝黻 北京市肿瘤防治研究所 
杨平 福建省莆田市医学科学研究所 
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中文摘要:
      福建省莆田市黄石乡是我国胃癌高发区之一。流行病学调查表明这与提供居民饮用水的木兰溪水系受严重污染有关。本文对32份沿此水系不同地点采集的冬、夏两季水样亚硝酸根及亚硝胺进行了测定。经GC-TEA和LC-TEA共检出6种致癌亚硝胺及3个非挥发性亚硝胺未知峰。冬季因受上游工厂污水的污染,水样中亚硝胺的种类及含量皆明显高于夏季,多层沙石过滤不能有效降低其含量。饮用水的亚硝胺污染可能与该地上消化道癌的高发有关。
英文摘要:
      Huang Shi town in Fujian province is one of the high-risk area of stomach cancer in China with a standard mortality rate of 61.19/100 000 in males.Epidemiologic survey showed that it was related to the severe contamination of Mu-Lan river system by which the drinking water for the residents was provided.
Thirth-three water samples in the summer and winter times, filtrated and unfiltrated, from different spots along this river system were collected. The concentrations of nitrite and nitrosamine were determined. NDMA, NDEA, NDPA, NDBA, NPIP and NMOR by GC-TEA and three unknow peaks preliminarily identified as non-volatile nitrosamine by LC-TEA could be detected in these samples. The kinds and the content of nitrosamine in the samples collected in the winter time were all significantly higher than those collected in the summer, P values were all less than 0.01. Its possible significance in the causes of gastrointestinal tumors is discussed.
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