| 李敬云,蒋豫图,王海涛,野京城.北京郊区某农村乙型肝炎病毒感染的随访研究[J].中华流行病学杂志,1991,12(6):321-324 |
| 北京郊区某农村乙型肝炎病毒感染的随访研究 |
| A Follow-up Study on HBV Infection in a Village of Beijing Rural Area |
| 收稿日期: 出版日期:2021-06-09 |
| DOI： |
| 中文关键词: 乙型肝炎病毒 随访 阴转 |
| 英文关键词: HBV Follow-up study Negative Conversion |
| 基金项目: |
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| 中文摘要: |
| 对北京郊区某农村的全体人口进行了乙型肝炎病毒(HBV)感染的6年随访调查(随访率78.4%)。发现HBsAg,抗-HBs,抗-HBc阴转率分别是每年2.9%,2.1%,1.2%。HBsAg和抗-HBs的阴转率似有随年龄增长而增加的趋势。滴度对标记的阴转有显著性影响,滴度越高,阴转率越低。抗-HBe阳性似乎有利于HBsAg、抗-HBs、抗-HBc保持稳定;抗-HBc阳性有利于抗-HBs保持稳定。可以认为,影响HBV感染标记转归的根本因素是HBV在体内复制的程度。HBV易感者在6年中有20.3%受到HBV的感染,大部分感染的来源似乎不是在家庭内。 |
| 英文摘要: |
| From 1982 to 1988, a follow-up study on HBV infection was carried out in a village of Beijing rural area. The negative conversion rates of HBsAg; anti-HBs; anti-HBc were 2.9%; 2.1%; 1.2% per year respectively. It was seemed that the negative conversion of HBsAg; anti-HBs increased with age. The present of anti-HBc was favourable to keeping anti-HBs. For all of the three markers, the higher the titre, the lower the negative conversion rates. It was concluded that the essential factor influencing the natural outcome of HBV markers was the level of HBV duplication. Those who were susceptible to HBV in 1982 were infected at the rate of 20.3%in this period. Analysis indicated that source of the Infection perhaps seems not to be in their family. |
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