阎永平,王珊珊,徐德忠,周华,陈友绩,王好善,李清甫,贾国法,王庆功,王广文.急性病毒性肝炎的病例对照研究与分型转归研究[J].中华流行病学杂志,1992,13(1):5-8 |
急性病毒性肝炎的病例对照研究与分型转归研究 |
Risk Factor for Acute Viral Hepatitis: A Case-Control Study |
收稿日期:1990-08-19 出版日期:2021-06-03 |
DOI: |
中文关键词: 甲型病毒性肝炎 乙型病毒性肝炎 非甲非乙型病毒性肝炎 病例对照研究 多因素分析 |
英文关键词: Hepatitis A Hepatitis B Non-A, non-B hepatitis Case-control study Multifactorial analysis |
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中文摘要: |
对两所医院162例急性病毒性肝炎患者进行了血清学分型和流行病学研究,并对发病的一些危险因素按成组和配对方法进行了病例对照研究。结果甲肝为37.0%,乙肝为40.7%,非甲非乙型肝炎为19.8%。经单因素和多因素Logistic回归分析,甲肝发病主要与肝炎接触史(OR=10.56)和不洁饮食史(OR=4.25)有关;乙肝与肝炎接触史(OR=4.30)和家庭成员既往肝炎史(OR=5.66)有关;非甲非乙型肝炎与肝炎接触史(OR=3.82)、输血史(OR=16.67)和既往肝炎史(OR=6.56)有关。甲肝、乙肝和非甲非乙型肝炎的转慢率分别为0%、12.1%和16.7%。 |
英文摘要: |
One hundred and sixty-two patients with acute viral hepatitis in two hospitals were studied between Jaunary and December, 1988. The risk factors, epidemiologic features and prognosis of those patients were investigated by case-control and follow-up study. Among the 162 patients, 37.0% were hepatitis A, 40.7%were hepatitis B, and 19.8% were non-A, nonB hepatitis:there were 4 cases of mixed infection and 3 cases of fulminant hepatitis not included in the study. By simple case-control and logistic regression analysis, the patients of hepatitis A more often had history of personal contact with hepatitis cases (OR=10.56) and of ingesting some contaminated foods (OR=4.25); hepatitis B more often had history of personal contact with hapatitis cases in their families or elsewhere (OR=5.66; OR=4.30 respectively), and hepatitis NANB more often had history of previous clinical hepatitis episode (OR=6.56), of personal contact with cases of hepatitis (OR=3.82) and of receiving a blood transfusion(OR=16.67).Among hepatitis A, B and NANB cases, sequelae of chronic hepatitis after acute phase were found in 0%, 12.1% and 16.7% of cases, respectively. |
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