文章摘要
阎永平,王珊珊,徐德忠,周华,陈友绩,王好善,李清甫,贾国法,王庆功,王广文.急性病毒性肝炎的病例对照研究与分型转归研究[J].中华流行病学杂志,1992,13(1):5-8
急性病毒性肝炎的病例对照研究与分型转归研究
Risk Factor for Acute Viral Hepatitis: A Case-Control Study
收稿日期:1990-08-19  出版日期:2021-06-03
DOI:
中文关键词: 甲型病毒性肝炎  乙型病毒性肝炎  非甲非乙型病毒性肝炎  病例对照研究  多因素分析
英文关键词: Hepatitis A  Hepatitis B  Non-A, non-B hepatitis  Case-control study  Multifactorial analysis
基金项目:
作者单位
阎永平 第四军医大学流行病学教研室 西安, 710032 
王珊珊 第四军医大学流行病学教研室 西安, 710032 
徐德忠 第四军医大学流行病学教研室 西安, 710032 
周华 第四军医大学流行病学教研室 西安, 710032 
陈友绩 第四军医大学流行病学教研室 西安, 710032 
王好善 解放军第150医院 
李清甫 解放军第150医院 
贾国法 解放军第150医院 
王庆功 解放军第371医院 
王广文 解放军第371医院 
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中文摘要:
      对两所医院162例急性病毒性肝炎患者进行了血清学分型和流行病学研究,并对发病的一些危险因素按成组和配对方法进行了病例对照研究。结果甲肝为37.0%,乙肝为40.7%,非甲非乙型肝炎为19.8%。经单因素和多因素Logistic回归分析,甲肝发病主要与肝炎接触史(OR=10.56)和不洁饮食史(OR=4.25)有关;乙肝与肝炎接触史(OR=4.30)和家庭成员既往肝炎史(OR=5.66)有关;非甲非乙型肝炎与肝炎接触史(OR=3.82)、输血史(OR=16.67)和既往肝炎史(OR=6.56)有关。甲肝、乙肝和非甲非乙型肝炎的转慢率分别为0%、12.1%和16.7%。
英文摘要:
      One hundred and sixty-two patients with acute viral hepatitis in two hospitals were studied between Jaunary and December, 1988. The risk factors, epidemiologic features and prognosis of those patients were investigated by case-control and follow-up study. Among the 162 patients, 37.0% were hepatitis A, 40.7%were hepatitis B, and 19.8% were non-A, nonB hepatitis:there were 4 cases of mixed infection and 3 cases of fulminant hepatitis not included in the study. By simple case-control and logistic regression analysis, the patients of hepatitis A more often had history of personal contact with hepatitis cases (OR=10.56) and of ingesting some contaminated foods (OR=4.25); hepatitis B more often had history of personal contact with hapatitis cases in their families or elsewhere (OR=5.66; OR=4.30 respectively), and hepatitis NANB more often had history of previous clinical hepatitis episode (OR=6.56), of personal contact with cases of hepatitis (OR=3.82) and of receiving a blood transfusion(OR=16.67).Among hepatitis A, B and NANB cases, sequelae of chronic hepatitis after acute phase were found in 0%, 12.1% and 16.7% of cases, respectively.
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