| 张堉,郑诚东,张代民,赵耀华.吸烟对健康人血清HDL-C等7项指标水平影响的对比观察[J].中华流行病学杂志,1992,13(2):97-100 |
| 吸烟对健康人血清HDL-C等7项指标水平影响的对比观察 |
| Influence of Smoking on Cholesterol Concentrations in Serum Lipo-protein of Healthy Subjects |
| 收稿日期:1990-03-07 出版日期:2021-06-03 |
| DOI： |
| 中文关键词: 吸烟 高密度脂蛋白胆固醇 低密度脂蛋白胆固醇 极低密度脂蛋白胆固醇 |
| 英文关键词: Smoking HDL-C LDL-C VLDL-C |
| 基金项目: |
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| 摘要点击次数: 1400 |
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| 中文摘要: |
| 经对生活和工作环境相似的40~69岁健康男性工人吸烟组697人和不吸烟组841人的对比观察,说明吸烟对健康人血清脂蛋白组分胆固醇水平有明显影响。吸烟组HDL-C、HDL2-C、HDL3-C、HDL2-C/HDL3-C明显低于不吸烟组,LDL-C、VLDL-C、LDL-C/HDL-C明显高于不吸烟组,且与吸烟量、时间、习惯呈剂量反应关系。吸烟是降低HDL-C、HDL2-C、HDL3-C、HDL2-C/HDL3-C和升高LDL-C、VLDL-C、LDL-C/HDL-C的危险因素。与不吸烟组相比,吸烟降低HDL-C等4项指标水平和升高LDL-C等3项指标水平的RR分别为1.09~5.77和2.37~3.59。被动吸烟者HDL-C等7项指标水平与轻度吸烟者相似,说明被动吸烟对血清脂蛋白组分胆固醇有明显影响。 |
| 英文摘要: |
| Sixty hundred and nineteen-seven smokers and 841 non-smokers among healthy male workers of 40~60 years of age were comparatively observed. Their housing environment and working conditions were similar.The results showed that smoking had remarkable influence on the cholesterol concentration in the serum lipo-protein of healthy subjects.The levels of HDL-C、HDL2-C、HDL3-C and HDL2-C/HDL3-C of the smoking group were obviously lower than those of the non-smoking group, while the levels of LDL-C、VLDL-C and LDL-C/HDL-C of the smoking group were obviously higher than those of the non-smoking group.Moreover, these indices were significantly associated with the smoking amount, smoking duration, depth of inhalation. Smoking was an important dangerous factor for lowering levels of HDL-C, HDL2-C、HDL3-C、HDL2-C/HDL3-C and raising levels of LDL-C、VLDL-C、LDL-C/HDL-C.The relative risk(RR) of the two factors were estimated to be 1.09~5.77 and 2.37~3.57 respectively.The levels of the 7 indices such as HDL-C of passive smokers were identical with those of light smokers. This showed that passive smoking also had marked influence on cholesterol concentrations in serum lipoprotein. |
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