| 山东省部分地区脊髓灰质炎监测与控制研究协作组.TOPV强化免疫效果的血清流行病学比较研究[J].中华流行病学杂志,1992,13(5):261-264 |
| TOPV强化免疫效果的血清流行病学比较研究 |
| A Comparison of the Effectivenes of Mass Immunization Campaign of Trivalent Oral Poliovirus Vaccine (TOPV) by Epidemiological Serosurvey |
| 收稿日期:1991-07-15 出版日期:2021-06-05 |
| DOI： |
| 中文关键词: 脊髓灰质炎口服活疫苗 强化免疫 血清流行病学 |
| 英文关键词: TOPV Mass immunization campaign Seroepidemiology |
| 基金项目: |
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| 中文摘要: |
| 以微量中和试验共检测902份TOPV强化免疫前后的血清标本。结果表明:强化免疫后临朐县和禹城县0~9岁儿童脊髓灰质炎Ⅰ、Ⅱ、Ⅲ型中和抗体之阳性率与几何平均滴度(GMT)均显著高于免疫前的结果。提示在抓好TOPV常规免疫的基础上,有必要开展强化免疫活动,以达到消灭脊髓灰质炎的目标。 |
| 英文摘要: |
| In order to evaluate the effect of TOPV mass immunization campaign, 902 serum samples from two counties of Shandong province were assayed by micro-neutralization test for the neutralization antibodies against poliovirus. The results showed that among children of 0 to 9 year-old groups, the antibody-positive rates and geometric mean titres (GMTs) with poliovirus type 1 to 3 after mass immunization campaign were significantly higher than those before the campaign, respectively. The auther cansiders that it is necessary for poliomyelitis eradication to carry out TOPV mass immunization campaign on the basis of EPI routine immunization. |
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