陈贤辉,胡真,柔玉莲,王健夫,杨天英,张巧云,朱宝兰,黄曼瑜.固相放射免疫分析法在流脑人群抗体监测及临床血清学诊断的应用研究[J].中华流行病学杂志,1993,14(6):366-370 |
固相放射免疫分析法在流脑人群抗体监测及临床血清学诊断的应用研究 |
Application of SP-RIA in the Antibody Surveillance and Serologic Diagnosis of Epidemic Cerebrospinal Meningitis |
收稿日期:1993-03-26 出版日期:2021-06-03 |
DOI: |
中文关键词: 流行性脑脊髓膜炎 固相放射免疫分析法(SPRIA) 血清学诊断 |
英文关键词: Neisseria Meningitis SP-RIA Serologic diagnosis |
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中文摘要: |
报导固相放射免疫分析法(SPRIA)在健康人群A群流脑血清APS-IgG抗体水平的监测、A群流脑菌多糖菌苗免疫持久性的观察以及临床血清学诊断的应用结果。同IHA、BCA和ELISA等常用的流脑抗体测定方法比较。SPRIA具有更好的特异性和敏感性,而且可以精确定量。显示SPRIA在流脑防治和科研工作中良好的实用价值。 |
英文摘要: |
This paper reports the effectness of SP-RIA in the antibody surveillance on population, the observation of immune persistence after vaccination with Group A Nesseria meningococcal capsular polysaccharide vaccine, as well as its use in the serological diagnosis of Nesseria meningitis. In comparison with other assays used presently, SP-RIA might be better and more sensitive for quantitative assay of the antibody. The results showed the practical value of SP-RIA in the study of epidemiology and serology of epidemic cerebrospinal meningitis. |
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