上海丹麦Ⅱ(D<sub>2</sub>)卡介苗菌株的免疫效果与反应

朱光辉; 陶鸿宝; 黄珍琴; 邱奕励

文章摘要

朱光辉,陶鸿宝,黄珍琴,邱奕励.上海丹麦Ⅱ(D₂)卡介苗菌株的免疫效果与反应[J].中华流行病学杂志,1994,15(2):80-82

上海丹麦Ⅱ(D₂)卡介苗菌株的免疫效果与反应

The Efficacy and side Reactions in Humans Immunized with Danish Strain of Dried BCG of Shanghai

收稿日期:1993-07-02 出版日期:2021-05-29

DOI：

中文关键词: 卡介苗菌株接种效果热稳定

英文关键词: BCG strain Efficacy of immunization Thermostability

基金项目:

作者	单位
朱光辉	卫生部上海生物制品研究所 200052
陶鸿宝	卫生部上海生物制品研究所 200052
黄珍琴	卫生部上海生物制品研究所 200052
邱奕励	卫生部上海生物制品研究所 200052

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中文摘要:

本文介绍了上海丹麦Ⅱ(D₂)菌株保存传代适应过程,及其对小鼠免疫保护率和人体接种阳转率与接种反应的情况,并推荐PB₃₀₂PSⅡ甲₁₀种子批菌种为我国统一菌株的候选茵种。

英文摘要:

A procedure of keeping Danish BCG strain 2 is reported. The strain is cultivated in Bile potato Medium and Suton Potato Medium alternatively with inocubation periods of two weeks. Lyophilized vaccine produced by using seeds derived from this strain gives better immunogenicity and lower side reaction to new-born babies and has better thermostability in compare with vaccines derived from strains of Beijing, Brazil, CCCP, France of Hungary

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