文章摘要
赵宁,俞顺章,孙伟明.肝癌危险因素的相互作用研究[J].中华流行病学杂志,1994,15(2):90-93
肝癌危险因素的相互作用研究
Interaction among the Relative Risk Factors of Primary Liver Cancer in A Case-Control Study
收稿日期:1993-07-03  出版日期:2021-05-29
DOI:
中文关键词: 肝癌  相互作用  危险因素
英文关键词: Primary hepatocellular carcinoma  Rik factors  Interaction
基金项目:
作者单位
赵宁 上海医科大学 200032 
俞顺章 上海医科大学 200032 
孙伟明 上海医科大学 200032 
摘要点击次数: 1248
全文下载次数: 452
中文摘要:
      笔者对原发性肝癌的主要危险因素饮水污染、乙型肝炎病毒感染、黄曲霉毒素污染间相互作用的关系进行了研究。运用相对危险度函数参数簇模型(从次相加结构到超相乘结构)来拟合病例对照资料,评判何种模型为佳,本文的结果提示:肝癌发生的主要危险因素饮水污染、乙型肝炎病毒感染、黄曲霉毒素(AFB1)污染间存在协同作用;AFB1与另两个肝癌主要危险因素乙型肝炎和饮沟塘水的联合作用似一种倾向于相加的结构,而乙型肝炎和饮沟塘水的联合作用似一种偏向于相乘的结构。不同模型间数量上的差别对病因学的解释和预防措施实践具有重要意义。
英文摘要:
      This paper evaluates the combined effect of HBsAg, drinking water and aflatoxin B1 (AFB1) on the primary hepatocellular carcinoma (PHC) in a case-control study which was carried out in Fusui, Guangxi. We used relative risk model (from subadditive to supermultiplicative) to fit the relationship. The results showed that the combined effect of HBsAg infection and drinking pond-ditch water is nearly multiplicative, and the combined effect of HBsAg infection and AFB1 intake as well as drinking pond-ditch water and AFB1 intake were nearly additive.
查看全文   Html全文     查看/发表评论  下载PDF阅读器
关闭