| 刘志广,姚凤鸣,张德恒,马克仁,杨华,孙文伟,郑扶民.吉林长白山敦化地区甲状腺疾病发病情况的研究[J].中华流行病学杂志,1997,18(1):30-32 |
| 吉林长白山敦化地区甲状腺疾病发病情况的研究 |
| Study on the Incidence of Thyroid Disease in Dun Hua District of Chang Bai Mountain Area, Jilin Province |
| 收稿日期:1996-03-04 出版日期:2021-06-08 |
| DOI： |
| 中文关键词: 甲状腺肿,地方性 甲状腺癌 |
| 英文关键词: Goiter, Endemic Carcinoma of thyroid |
| 基金项目: |
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| 中文摘要: |
| 对长白山敦化地区原地方性甲状腺疾病（简称地甲病）高发区，食用加碘盐后10年甲状腺疾病发病情况进行调查，结果地甲病发病率有所下降，但仍为10.4%；而甲状腺癌发病率上升为1.9%，甲状腺炎上升为0.85%，地方性甲状腺肿的病理特征多为腺癌样甲状腺肿改变，在纤维化区出现一些易癌变的不典型增生的滤泡。发现目前地甲病的发生除了碘盐加碘量不足外，也与碘排出量相对增加有关，碘排出量增加可能与副食蔬菜种类及饮食习惯有关。 |
| 英文摘要: |
| Dun Hua is a district where endemic goiter has been prevalent. Residents commenced to eat iodined salt ten years ago. We studied 469 people in this district and discovered that the incidence of endemic goiter had somehow come down but still kept 10.4%. However, the incidence of thyroid cancer went up to 1.9% with the incidence of thyrioditis 0.85%. Pathological characteristic of endemic goiter frequently appeared adenoniatoid feature with some atypical hyperplasia follicles which facilitates the cancerization in the fibrigenic part. Reasons accounted for the endemic goiter occurrance might not only relate to the insufficient intake of iodined salt but also to the increase of iodine excretion from the body.The increase of iodine excretion may be related to the factors as varieties of subsidiary food and vegetables as well as personal habitualness on food and drinks. |
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