文章摘要
俞顺章,资晓林,陈刚,李迥.我国四个地区肝炎病毒感染与肝癌的病例对照研究[J].中华流行病学杂志,1997,18(4):214-216
我国四个地区肝炎病毒感染与肝癌的病例对照研究
The Relationship between Viral Hepatitis and Primary Liver Cancer in Four Areas of China
收稿日期:1997-02-24  出版日期:2021-06-09
DOI:
中文关键词: 乙型肝炎;丙型肝炎;庚型肝炎;肝癌
英文关键词: Hepatitis B;Hepatitis C;Hepatitis G;PLC
基金项目:
作者单位
俞顺章 上海医科大学预防医学研究所 200032 
资晓林 上海医科大学预防医学研究所 200032 
陈刚 上海医科大学预防医学研究所 200032 
李迥 上海医科大学预防医学研究所 200032 
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中文摘要:
      为研究乙型、丙型和庚型肝炎与原发性肝癌的关系,对我国江苏海门、福建同安、广西扶绥和河北石家庄四地,进行了以人群或医院为基础的肝癌病例对照研究。在四个地区病例与对照中,HBsAg阳性率分别为66.3%(238/359)和23.4%(84/359),其OR值为6.60;抗-HCV阳性率分别为17.9%(61/340)和6.5%(22/340),OR=3.31;合并乙丙型肝炎感染其肝癌危险度大大增加(OR=110.08)。另对海门病例对照各50例进行HGV-RNA检测,阳性率分别为22%和10%。结果说明:在我国乙型肝炎感染与肝癌关系更为密切。
英文摘要:
      To investigate the relationship between hepatitis B,C and G and primary liver cancer (PLC),both population based and hospital based case control studies were conducted in four areas of China. The prevalence rates of HBsAg in 359 pairs of PLC cases and controls were 66.3% and 23.4% (OR=6.60,PAR=55.5%),respectively;the prevalence of anti HCV in 340 pairs of PLC cases and controls were 17.9% and 6.5% (OR=3.31, PAR=12.4%),respectively.When both markers were positive, the OR was higher than their multiple effect of HBsAg and anti HCV.In the Haimen Case control study,serum HGV RNA was detected in 11 of the 50 PLC cases,compared to 5 of the 50 controls matched with age and sex (P > 0.05).These data suggested that HBV might have played a more important role than HCV and HGV in the development of PLC in China.
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