文章摘要
卢桂静,郑昭芬,张利辉,欧淑其,夏斌赞,刘庆武.米力农治疗严重充血性心力衰竭患者的心功能及临床观察[J].中华流行病学杂志,1998,(1):27-28
米力农治疗严重充血性心力衰竭患者的心功能及临床观察
Heart Function and Clinical Observations of Patients with Severe Congestive Heart Failure Treated with Milrinone
  
DOI:
中文关键词: 米力农;心力衰竭;充血性
英文关键词: Milr inone; Congestive heart failure
基金项目:
作者单位
卢桂静 湖南医科大学湘雅医院心内科, 长沙 410008 
郑昭芬 湖南医科大学湘雅医院心内科, 长沙 410008 
张利辉 湖南医科大学湘雅医院心内科, 长沙 410008 
欧淑其 湖南医科大学湘雅医院心内科, 长沙 410008 
夏斌赞 湖南医科大学湘雅医院心内科, 长沙 410008 
刘庆武 湖南省郴州高等医学专科学校 
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中文摘要:
      观察25 例严重充血性心力衰竭患者静脉注射国产米力农15 天后对心功能影响。结果: 显效率60%, 总有效率96%, 治疗前后用脉冲多普勒和M 型超声心动图测定其心功能及左房、左室、右室内径。治疗后, 左室收缩功能( 如每搏量、心排血量、射血分数、左室短轴缩短率、室间隔和左室后壁增厚率) 明显改善| 而左室舒张功能( 如早期血流峰值速度, 晚期血流峰值速度及等容舒张期) 得到改善| 左房、左室及右室内径缩小| 心率, 血压无明显变化。治疗过程中未发现严重的副作用。提示国产米力农是治疗严重充血性心力衰竭患者的有效药物。
英文摘要:
      To evaluate the clinical effects of milrinone in patients with severe heart failure, heart function and clinical obser vations were performed on 25 patients with severe cong estive heart failure treated with domestic intravenous milrinone for 15 days. Results showed that the total response rate to milrinone was 96% while 60% of them had significant improvement. Heart function and diameter of left atrial, left ventricle, and right ventricle were measured by pulsed Doppler and M-mode echocar diographg before and after the treatment. The systolic function of the left ventricle ( such as SV, CO, EF, FS,IVST, PLVWT ) was significantly improved. The diastolic function of the left ventricle ( such as E peak, A peak, IRT ) was also improved. Diameter of left atrial, left ventricle, and right ventricle was significantly reduced. The heart rate and blood pressure remained unchanged. No obvious side-effect was found in our observation. The domestic intravenous milrinone is a drug of choice for the management of patients with severe cong estive heart failure.
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