文章摘要
汪治中,卫连坤,牟贤龙,吴寅华,薛广波,蔡全才.颧部褐青色痣危险因素的病例对照研究[J].中华流行病学杂志,1999,20(2):102-103
颧部褐青色痣危险因素的病例对照研究
A case-control study on the risk factors in naevus fusco-caeruleus zygomaticus
收稿日期:1998-06-27  出版日期:2014-09-16
DOI:
中文关键词: 痣,褐青色;病例对照研究;危险因素
英文关键词: Naevus,fusco-caeruleus;Case-control study;Risk factor
基金项目:
作者单位
汪治中 第二军医大学长海医院皮肤科, 上海200433 
卫连坤 第二军医大学长海医院皮肤科, 上海200433 
牟贤龙 第二军医大学长海医院皮肤科, 上海200433 
吴寅华 第二军医大学长海医院皮肤科, 上海200433 
薛广波 第二军医大学流行病学教研室 
蔡全才 第二军医大学流行病学教研室 
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中文摘要:
      目的 探讨颧部褐青色痣的发病危险因素。>方法 对100例患者进行1:1配对的病例对照研究,通过条件logistic回归多因素和单因素分析筛选主要危险因素。结果 该病患者有较高的家族史暴露率,提示该病有“遗传易感性”存在。环境危险因素有化妆品应用史和紫外线暴露史,但每一因素均不能解释所有病例。结论 认为遗传易感性与环境危险因素的联合作用可以解释颧部褐青色痣的发病过程,遗传基因的定位与环境因素的联合研究对揭示颧部褐青色痣的病因具有重要意义。
英文摘要:
      ObjectiveTo determine the risk factors of naevus fusco-caeruleus zygomaticus,a case-control study was conducted in 100 cases.Methods The selection of major risk factors was through logistic regression and χ2-test.Results It was suggested that the high exposed rate in the family history of objectives was related to “ genetic susceptibility”.Histories of using cosmetics and exposure to ultraviolet ray were identified as enviromental risk factors.However,there was no single factor that could completely explain the etiology of naevus fusco-caeruleus zygomaticus.ConclusionWe believe that coordinating effects of both susceptibility in genetics and enviromentalrtant in the discovery of the etiology of naevus fusco-caeruleus zygomaticus.
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