文章摘要
凌斌华,庄辉,李奎,杨永芳,李盛,马为民,王跃民.我国不同人群输血传播病毒感染调查[J].中华流行病学杂志,1999,20(5):277-279
我国不同人群输血传播病毒感染调查
Detection of transfusion transmitted virus(TTV)in different populations of China
收稿日期:1999-03-26  出版日期:2014-10-17
DOI:
中文关键词: 输血传播病毒;聚合酶链反应;肝炎病毒非甲-庚型
英文关键词: Transfusion transmitted virus(TTV);Polymerase chain reaction(PCR);Non A-E hepatitis virus
基金项目:
作者单位
凌斌华 北京医科大学微生物学系,100083 
庄辉 北京医科大学微生物学系,100083 
李奎 北京医科大学微生物学系,100083 
杨永芳 云南省卫生防疫站 
李盛 安徽医科大学 
马为民 深圳市东湖医院 
王跃民 青岛市疾病控制中心 
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中文摘要:
      目的:了解不同人群输血传播病毒 (TTV)的感染状况。方法:采用套式PCR法检测血清标本中TTVDNA,并对其中 1株TTV的部分基因序列进行了测定。结果:不同人群TTVDNA阳性率分别为:正常体检人群 10.3%,献血员 43.7%,吸毒者 15.6%,血液透析病人5 4.4%,妓女 65.0%,慢性丙型肝炎病人 2 5.0%,非甲~庚型肝炎 0/ 11。结论:TTV在各类人群中均有较高的感染率.
英文摘要:
      Objective:To investigate the prevalence of transfusion transmitted virus(TTV)in different populations of China.Methods: TTV DNA was detected in sera collected from different populations by nested PCR.Partial gene of a TTV isolate was directly sequenced.Results:The prevalences of TTV in various populations were as follows:10.3%(31/301)in general population when receiving physical checkup;43.7%(14/32)in blood donors;15.6%(5/32)in intravenous drug addicts;54.4%(6/11)in hemodialysis patients;65%(13/32)in prostitutes;25%(4/16)in patients with chronic hepatitis C.None of the 11 patients with non A-G hepatitis was detected TTV DNA.Conclusion:High prevalence of TTV infection was found in different populations of China.
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