文章摘要
王育琴,王力红,徐燕侠,王淑洁,王佳麟,姜萍,李非,石海鸥,王海莲,张京利,陈莲珍,刘江,王青.Ⅰ、Ⅱ类切口围手术期抗菌药物合理应用的干预对照研究[J].中华流行病学杂志,2002,23(4):301-303
Ⅰ、Ⅱ类切口围手术期抗菌药物合理应用的干预对照研究
Study on intervention and comparison of rational use of antibiotics on perioperative period of clean incision and clean-defiled incision
收稿日期:2002-03-19  出版日期:2014-09-18
DOI:
中文关键词: 围手术期;抗菌药物;合理用药;干预对照研究
英文关键词: Perioperative period Antibiotics Rational drug use Intervention and comparison research
基金项目:
作者单位
王育琴 首都医科大学宣武医院药剂科, 北京 100053 
王力红 首都医科大学宣武医院药剂科, 北京 100053 
徐燕侠 首都医科大学宣武医院药剂科, 北京 100053 
王淑洁 首都医科大学宣武医院药剂科, 北京 100053 
王佳麟 北京友谊医院 
姜萍 首都医科大学宣武医院药剂科, 北京 100053 
李非 首都医科大学宣武医院药剂科, 北京 100053 
石海鸥 首都医科大学宣武医院药剂科, 北京 100053 
王海莲 首都医科大学宣武医院药剂科, 北京 100053 
张京利 首都医科大学宣武医院药剂科, 北京 100053 
陈莲珍 首都医科大学宣武医院药剂科, 北京 100053 
刘江 北京友谊医院 
王青 国家药品监督管理局药品评价中心 
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中文摘要:
      目的探讨围手术期抗菌药物应用的评价与干预措施实施的可行性。方法选取两家三级甲等医院,分设干预组、非干预组,对干预前后同期出院的甲状腺、乳腺、腹腔镜胆囊切除术、经腹子宫肌瘤和子宫肌瘤 +附件手术病例,进行干预对照研究。结果干预后干预组平均药费由1601.27元下降为1489.59元、抗菌药平均费用由740.20元下降为352.03元 (P<0.01);使用抗菌药物的合理率(合理 +基本合理)有显著提高,由干预前的 31.35%上升为干预后的91.81%(P <0.01)。结论实施的合理用药措施具有可行性和有效性,对促进安全、有效、经济地使用抗菌药物起到了积极的促进作用
英文摘要:
      Objective To explore a set of scientific evaluation and intervention methods on perioperatur period which fits for China's situation, and to promote the development of rational drug use. Methods Two would tertiary general hospitals were selected and separated in to intervention group and control group. Intervention was carried out and compared at the same period on inpatient surgical cases of thryroidectomy, mastectomy, cholescystectomy, and hysteromyomectomy plus appendix. Results The average drug costs was decreased from 1 601.27 yuan to 1 489.59 yuan and the average antibiotics use from 740.20 yuan to 352.03 yuan ( P 0.01 ) in the intervention group pre and post intervention. There was a remarkable improvement on the rationality of antibiotics use in intervention group, from 31.35 % to 91.81 % ( P 0.01 ) pre and post intervention, implemented in the hospital. Conclution It is practicable and effective to implement rational drug use where intervention was carried out, since it plays an active role on promoting safely, effectively and economic antibiotic use in China.
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