| 杨少泉,张秀美,胡秀云,范其芬,刘金美.某矿业集团35年工伤事故发生时间分布规律的调查[J].中华流行病学杂志,2003,24(6):461 |
| 某矿业集团35年工伤事故发生时间分布规律的调查 |
| A study on acute renal failure after an outbreak of diarrhea in Suixian county, Henan province |
| 收稿日期:2003-02-13 出版日期:2014-09-18 |
| DOI： |
| 中文关键词: 大肠杆菌O157：H7 溶血性尿毒综合征 聚合酶链反应 |
| 英文关键词: Escherichia coli O157：H7 Hemolytic uremic syndrome Polymerase chain reaction |
| 基金项目: |
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| 中文摘要: |
| 工伤事故严重威胁着工人的人身安全. 作者对山东新汶矿业集团12个煤矿35年所发生的工伤事故进行了回顾性调查. |
| 英文摘要: |
| Objective To study the distributional feature and clinical characteristics of infectious diarrhea caused by enterohemorrhagic Escherichia coli O157：H7, and to understand its pollution to the environment and the carrier status among livestock and poultry. Methods To describing the incidence of diarrhea, to isolate and culture the pathogenic bacteria from samples of the patients with diarrhea and livestock or poultry with Methods of microbiology, molecular biology and cytology, and then to determine the toxic factors. Results In the first epidemic area in Suixian county, Henan province, 35 cases had been found during 17 March and 6 July with 91% of them above age of 60. Of them, 32 were complicated with acute renal failure, including 28 death (death rate: 87.50%). One hundred and seven strains of O157：H7 were isolated from the samples of livestock or poultry and 48 strains were isolated from patients. It was found that 67 strains having toxic gene through microbiological, molecular biological and cytological technologies. Five types of toxic factors were found. Conclusion The main factor causing death was the complicated acute renal failure from diarrhea infected by E. coli O157：H7. The pathogen from livestock or poultry with high carrying rate might infect people through polluted water, food flies and close contacts. The outbreak of acute hemolytic uremic syndrome in Suixian county was caused by Enterohemorrhagic Escherichia coli O157：H7 infection. |
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