文章摘要
周畔,陈恩国.肺机械通气患者醋酸钙不动杆菌引起的呼吸机相关性肺炎危险因素的分析[J].中华流行病学杂志,2004,25(7):617-619
肺机械通气患者醋酸钙不动杆菌引起的呼吸机相关性肺炎危险因素的分析
A prospective study on the risk factors of Acinetobacter banmannii bacteremia infection in incubated patients with nosocomial pneumonia
收稿日期:2003-12-25  出版日期:2014-09-17
DOI:
中文关键词: 肺炎;肺机械通气;病原菌;危险因素
英文关键词: Pneumonia;Pulmonary ventilators;Bacteria;Risk factor
基金项目:
作者单位
周畔 浙江大学医学院附属邵逸夫医院呼吸科 杭州 310016 
陈恩国 浙江大学医学院附属邵逸夫医院呼吸科 杭州 310016 
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中文摘要:
      目的 调查呼吸机相关性肺炎(VAP)患者醋酸钙不动杆菌感染的流行病学特点.方法前瞻性临床研究分析邵逸夫医院重症监护病房176例连续性发生VAP的病原学诊断结果.分成醋酸钙不动杆菌组和对照组(其他致病茵),用多元logistic回归法分析醋酸钙不动杆菌引起VAP的危险因素.结果 醋酸钙不动杆菌组26例(26/176,14.7%),对照组150例(85.2%).统计学分析表明,头颅外伤(OR=4.20,95%CI:2.72~6.48)、外科手术(OR=2.88,95%CI:1.78~4.66)、成人呼吸窘迫征(OR=2.81,95%CI:1.19~6.64)、大量肺误吸(OR=6.71,95%CI:3.91~11.50)是患者并发醋酸钙不动杆菌VAP的高危因素.结论 使用呼吸机的患者感染醋酸钙不动杆菌引起VAP,其流行病学特点不同于其他致病菌,高危因素可能是气道护理时的交叉感染.
英文摘要:
      Objective To study the epidemiology of Acinetobacter baumannii infection in patients with ventilator-associated pneumonia(VAP).Methods Prospective clinical study was carried out with 176 episodes of VAP with etiologic diagnosis being followed in two groups.Results Twenty-six episodes were caused by Acinetobacter baumannii and one hundred-fifty episodes were caused by"other"organisms.Using logistic regression analysis.the risk of VAP due to Acinetobacter baumannii was found to be high in patients with head trauma[odds ratio(OR)=4.20,95% confidence interva(CI):2.72 to 6.48),surgery(OR=2.88, 95%CI:1.78 to 4.66),acute respiratory dispnea syndrom(OR=2.81,95%CI:1.19 to 6.64),and large-volume pulmonary aspiration(OR=6.7 1.95%CI:3.91 to 11.50).Conclusions Acinetobacter baumannii pulmonary infection in incubated patients had an epidemiologica1 pattern that different from "other"organnisms.Patients with high risk identified in our study might mark the existence of cross-infection during airway manipulation.
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