文章摘要
李凯骐,张建军,卢白莉,刘连忠,刘光忠,尹平.武汉市中学生使用苯二氮卓类药物的流行病学调查[J].中华流行病学杂志,2005,26(8):596-599
武汉市中学生使用苯二氮卓类药物的流行病学调查
Study on the use of benzodiazepine among middle school students in Wuhan city
收稿日期:2004-08-06  出版日期:2014-09-18
DOI:
中文关键词: 苯二氮卓;中学生;流行病学调查
英文关键词: Benzodiazepine Middle school;students Epidemiologic;research
基金项目:武汉市卫生局科研基金资助项目[武卫1999(237)]
作者单位
李凯骐 武汉市精神病医院 430022 
张建军 武汉市精神病医院 430022 
卢白莉 武汉市精神病医院 430022 
刘连忠 武汉市精神病医院 430022 
刘光忠 武汉市教育局 
尹平 华中科技大学同济医学院 
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中文摘要:
      目的了解武汉市初、高中学生使用苯二氮卓(BZD)类药物的现状。方法于2002年调查武汉市七个中心城区。每个区随机抽取4所普通中学,共28所中学;每个学校调查初二、初三、高一、高二、高三等五个年级,每个年级按偶数抽取二、四、六、八……班,共258个班,获有效问卷12345份。采用自行设计的匿名式自填问卷。调查数据采用SPSS10.0软件进行统计。结果调查发现武汉市中学生BZD类药物的使用率为4.0%,依赖倾向的发生率为4.1‰。全市服药的学生在性别、年级上存在差异性:男生高于女生(P<0.01),高中生高于初中生(P<0.01)。最常用的药物为安定(59%)和硝基安定(29.7%)。服药时间1-7天者占43.3%,6个月以上者为8.2%。服药原因占首位的是失眠(43%),其次是学习压力大(25%)。而BZD类药物滥用的主要原因则是:摆脱烦恼(14.1%)、好奇(13.3%)、受周围人影响(10.8%)、寻求快乐(9.85%)等。药物来源29%是从家中得到。多元logistic回归分析发现:要遵医嘱、性别、经常喝酒、好玩可服和有益无害、经常抽烟、我与父母关系、母亲教育方式、父亲文化水平、父母间关系、年级等是BZD类药物滥用的危险因素。结论武汉市中学生有使用BZD类药物的现象,使用BZD类药物是个人、家庭、社会多因素的结果。
英文摘要:
      Objective In order to understand the status of benzodiazepine(BZD) use in middle-school students from Wuhan city. Methods In the Wuhan city zone, twenty-eight middle-schools were chosen randomly to the even numbers, with students from grade 8 to 12 had been studied. Altogether, 258 classes were investigated with 12 345questionnaires were filled in by the subjects anonymously. SPSS 10.0was used for data analysis. Results Rate of BZD use in Wuhan middle school students was 4.0% with the rate of dependence as 4.1‰. There were differences in gender and grade:male students tend to be higher than females( P 0.01), and senior higher than junior's( P 0.01). More commonly used drugs would include Diazepam(59%) and Surazepam( 29.7%). Among students who used drugs, 43.3% used for 1-7 day and 8.2% of them used 6 tablets or more. 57.6% used 1 tablet once a day( 46.2%) before bed time( 40.8%). The major reason for using drug was insomnia(43%), followed by pressure from school. The reasons for BZD abuse were:relief of anxiety( 14.1%), curiosity( 13.3%), peer pressure( 10.8%), and fun seeking( 9.85%), etc. The source of drugs was from their families(29%). By Multinomial logistic regression, the risk factors of abuse BZD were:ignorance of drug prescription, sex, regular alcohol intake, knowing that BZD use can bring amusement regular, smoking cigarettes, relationship with parents, mother's way of providing education, schooling of fathers, relationship between parents. Conclusion Difference wasseen in the use of BZD between gender and age of the students. Multiple factors showed that:personal, family and social factors were related to the use of BZD.
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