| 边归国.儿童血铅与室内尘埃中铅的化学形态相关性研究[J].中华流行病学杂志,2009,30(4):356-359 |
| 儿童血铅与室内尘埃中铅的化学形态相关性研究 |
| Association of child blood lead and its chemical form in the room dust |
| 收稿日期:2008-09-16 出版日期:2014-09-17 |
| DOI： |
| 中文关键词: 儿童血铅 化学形态 暴露量 摄入量 |
| 英文关键词: Child blood lead Chemical form Exposure Intake |
| 基金项目: |
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| 中文摘要: |
| 研究儿童血铅与室内尘埃中铅的化学形态相关性，探索其可移动性和生物有效性。方法采用分步提取法分析测试室内尘埃中铅的7种化学形态，从环境到血铅分4个环节分析计算室内尘埃中铅的腐殖酸结合态、碳酸盐结合态的暴露量、摄入量、溶出量与儿童血铅的关联。结果儿童血铅与各化学形态均呈正相关，但差异有统计学意义的只有碳酸盐态(r=0.531，P<0.01)和腐殖酸态(r=0.361，P<0.05)，与碳酸盐态的暴露量(碳酸盐态r=0.837，P<0.01)、摄入量(碳酸盐态r=0.838，P<0.01)和模拟胃酸溶出量(碳酸盐态pH值3.5时r=0.837，P<0.01)非常显著相关，与腐殖酸态的暴露量(r=0.746，P<0.05)、摄入量(r=0.746，P<0.05)和碳酸盐态模拟胃酸溶出量(pH值1.5时r=0.745，P<0.05)显著相关。结论在中国南方碳酸盐态铅含量较高的地区，碳酸盐态和腐殖酸结合态铅可能是造成儿童血铅超标的主要原因。 |
| 英文摘要: |
| Studies on the association of child blood lead and the chemical form of the room dust lead as well as to explore its removability and the biological validity.Methods Using minute step extraction process to analyze and test the seven chemical forms of lead in the dust of a room.Blood lead count and humus union condition,carbonate union condition exposition quantity,amount of radiation,output quantity from environmental to blood lead etc.were calculated.Results The child blood lead was related to the various chemical form but carbonate condition (r=0.531,P<0.01) and humus (r=0.361,P<0.05) showing statistical significance and also related to the exposure of carbonatecondition (carbonate：r=0.837,P<0.01).The output quantity (carbonat pH=3.5：r=0.837,P<0.01 )of simulate gastric juice was related to the exposure to humus (r=0.746,P<0.05),intake (r=0.746,P<0.05) and the output quantity of carbonate condition simulate gastric juice (pH=1.5：r=0.745,P<0.05).Conclusion In South China,areas with high carbonate content lead and the union conditions of carbonate and humus were possibly the main reasons causing excessive amount of child blood lead level. |
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