文章摘要
张波,蔡莉,苏萌,周晓星,黄莉莉,陈超刚,甘人友,陈若青,苏宜香.广州市40~65岁中老年人膳食大豆异黄酮摄入与血脂关系的横断面研究[J].中华流行病学杂志,2009,30(8):761-765
广州市40~65岁中老年人膳食大豆异黄酮摄入与血脂关系的横断面研究
Relationship between dietary soy isoflavones and blood lipid levels in 40-65 year-olds in Guangzhou
收稿日期:2009-02-17  出版日期:2014-09-12
DOI:
中文关键词: 血脂  大豆异黄酮  食物频数问卷
英文关键词: Blood lipids  Soy isoflavone  Food-frequency questionnaire
基金项目:
作者单位E-mail
张波 中山大学公共卫生学院营养系, 广州, 510080  
蔡莉 中山大学公共卫生学院营养系, 广州, 510080  
苏萌 中山大学公共卫生学院预防医学系, 广州, 510080  
周晓星 中山大学公共卫生学院营养系, 广州, 510080  
黄莉莉 中山大学公共卫生学院营养系, 广州, 510080  
陈超刚 中山大学公共卫生学院附属第二医院营养科, 广州, 510080  
甘人友 中山大学公共卫生学院营养系, 广州, 510080  
陈若青 中山大学公共卫生学院预防医学系, 广州, 510080  
苏宜香 中山大学公共卫生学院营养系, 广州, 510080 suyx@mail.sysu.edu.cn 
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中文摘要:
      目的 研究广州市中老年人大豆异黄酮摄入与血脂的关系.方法 用食物频数问卷分析395名40~65岁广州市居民每日大豆异黄酮及其他食物和营养素的摄入量,抽取空腹静脉血测定血脂.结果 134名男性和261名女性的大豆异黄酮摄入分别为11.95(0~61.96)mg/d和14.90(0~82.52)mg/d.按照大豆异黄酮摄入量将研究对象等分为低、中、高三组,在校正了总能量摄入和脂肪供能比后,三组间TC、LDL-C差异有统计学意义(P值分别为0.002、0.008),并存在剂量效应关系(趋势分析P值分别为<0.001、0.012);高摄入组与低摄入组相比,TC、LDL-C分别下降7.06%、10.13%.在进一步校正年龄、BMI和腰臀比后,上述结果无明显改变.结论 膳食大豆异黄酮摄入与血浆TC、LDL-C负相关.
英文摘要:
      Objective To study the mlationship between dietary soy isoflavones and blood lipids among residents of 40-65 years old,in Guangzhou.Methods Dietary soy isoflavones and other nutrients intakes were assessed with quantitative food frequency questionnaire(FFQ).Total cholesterol(TC),triglycerides(TG),HDL cholesterol(HDL-C)and LDL cholesterol(LDL-C)in plasma were measured with colorimetry.Results Ranges of dietary soy isoflavones intake among 134 males and 261 females were fxom 0 mg/day to 61.96 mg/day and 0 mg/day to 82.52 mg/day,with means of 11.95 mg/day,14.90 mg/day,respectively.After adjusted for total energy intake and fat percent energy,difiefences of TC,LDL-C in total population and TC in women were statistically significant between groups(P value was 0.002,0.008,0.004,respectively) and dose-effect relationships(P value was <0.001.0.012.0.001,respectively)were observed between dietary soy isoflavones intake and the upper mentioned three indices.Compared with the low-intake group,tbese three indices lowered 7.06%,10.13%and 7.48%,respectively in high-intake group.Critical significance of LDL-C was observed both in women and men between groups.Further controlled for age,BMI and WHR,no obvious change of the results was observed.Conclusion Moderate intakes of soy isoflavone as part of a regular diet seemed to be associated with favorable blood lipid levels.
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