| 史晓红,荀健,王素萍,张晶.212例慢性病毒性肝炎患者抑郁症状发生的现状分析[J].中华流行病学杂志,2009,30(10):1060-1064 |
| 212例慢性病毒性肝炎患者抑郁症状发生的现状分析 |
| Study on depression in 212 patients with viral hepatitis |
| 收稿日期:2009-04-21 出版日期:2014-09-18 |
| DOI： |
| 中文关键词: 病毒性肝炎 抑郁 |
| 英文关键词: Viral hepatitis Depressive |
| 基金项目:国家"十一五"科技支撑项目(2006BAI02B08) |
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| 中文摘要: |
| 目的了解慢性病毒性肝炎患者抑郁症状发生的现状.方法 以慢性乙型、丙型肝炎患者作为研究对象,采用问卷调查的方法,用自制的慢性病毒性肝炎问卷调查表、抑郁症状自评量表(SDS)、艾森克人格问卷等对慢性病毒性肝炎患者抑郁症状情况及相关因素进行调查.应用SPSS 13.0软件进行统计分析.结果212例慢性病毒性肝炎患者抑郁症状的检出率为54.7%,SDS评分为39.08±11.16.不同年龄、职业、文化程度抑郁症状的检出率不同,差异有统计学意义(χ~2=32.24,P<0.000;~2=22.59,P<0.000;χ~2=23.304,P<0.000);病毒性肝炎分度、感染时间、确诊时间、肝炎复发次数、抗病毒治疗时间不同,抑郁症状的检出率不同,差异有统计学意义(χ~2=15.136,P=0.001;χ~2=32.737,P<0.000;χ~2=9.401,P=0.009;χ~2=10.734,P=0.005;χ~2=30.353,P<0.000);患者对治疗的信心、对周围态度满意程度不同抑郁症状检出率不同,差异有统计学意义(χ~2=12.715,P<0.01;χ~2=9.456,P<0.01).SDS总分与社会支持总分、客观支持维度分值、主观支持维度分值之间呈负相关关系,差异有统计学意义(r=-0.262,P=0.000;r=-0.228,P=0.001;r=-0.270,P=0.000).SDS总分与艾森克人格评分内外向维度分值之间呈显著负相关,差异有统计学意义(r=-0.330,P=0.000),与情绪稳定性分值维度之间呈显著正相关,差异有统计学意义(r=0.309,P=0.000).结论 (1)慢性病毒性肝炎患者抑郁症状的检出率为54.7%.(2)是否出现抑郁症状可因患者年龄、职业、文化程度、肝炎分度、感染时间、诊断时间、复发次数、抗病毒治疗时间、收入、支付方式、及对治疗信心和对周围态度的满意程度的不同而不同.(3)患者获得的支持度越低,SDS总分越高,抑郁程度越重;个性越倾向内向,SDS总分越高,抑郁程度越重;情绪越不稳定,SDS总分越高,抑郁程度越重. |
| 英文摘要: |
| Objective To investigate the symptoms on depression in patients with viral hepatitis. Methods A cross-sectional study was conducted among the patients with viral hepatitis in infectious diseases Hospital of Taiyuan. The questionnaire included a Eysenck Personality Questionnaire, self-rating depression scale (SDS), and a self-designed one related to information regarding general conditions of the disease and social support. Results (1)Depression symptom prevalence rate among chronic viral hepatitis patients was 54.7% (116/212). (2) Factors as age, occupation, education, confirmed time, number of recurrence and anti-virus treatment, self-confidence on recovery, satisfaction on the surrounding environment etc. that might be associated with depression. (3) The severity of depression was significantly negative correlation with social support scores, Objective support scores, subjective support scores (r=-0.262, P=0.000;r=-0.228, P=0.001 ; r=-0.270, P=0.000). (4) There was positive correlation noticed between severity of the depressive disorder and Eysenck Personality two dimensions scores, while the scores of introversion and extroversion scores were negatively correlated (r=-0.330, P=0.000) but positively correlated to the emotional stability scores (r=0.309, P=0.000). Conclusion (1) Patients with hepatitis showed symptoms of depression to a certain degree. (2) Factors as age, occupation, education, economic situation, confirmed time of diagnosis, number of recurrence and anti-virus treatments, confidence on recovery, satisfaction on the surrounding environment might be associated with symptoms of depression. (3) There was positive correlation between severity of depressive and Eysenek Personality two dimensions scores but the scores of introversion and extroversion scores were negatively correlated. |
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