北京市怀柔区儿童维生素D营养状况及其与体成分的关系

赵静; 张倩; 张环美; 郭宏霞; Rickard0ste; 郝利楠; Gunilla Onning; Lena Hulthén; 胡小琪

文章摘要

赵静,张倩,张环美,郭宏霞,Rickard0ste,郝利楠,Gunilla Onning,Lena Hulthén,胡小琪.北京市怀柔区儿童维生素D营养状况及其与体成分的关系[J].中华流行病学杂志,2010,31(1):34-38

北京市怀柔区儿童维生素D营养状况及其与体成分的关系

Body vitamin D content and its relationship with body composition of children in Huairou district of Beijing

收稿日期:2009-05-13 出版日期:2014-09-12

DOI：

中文关键词: 维生素D缺乏儿童体成分 25一羟维生素D

英文关键词: Vitamin Ddeficiency Child Body composition 25一hydroxyvitamin D

基金项目:

作者	单位	E-mail
赵静	100050 北京, 中国疾病预防控制中心营养与食品安全所
张倩	100050 北京, 中国疾病预防控制中心营养与食品安全所
张环美	瑞典隆德大学化学与化学工程系
郭宏霞	四川大学华西公共卫生学院
Rickard0ste	瑞典隆德大学食品化学与应用营养系
郝利楠	100050 北京, 中国疾病预防控制中心营养与食品安全所
Gunilla Onning	瑞典隆德大学化学与化学工程系
Lena Hulthén	瑞典哥德堡大学健康科学研究院临床营养系
胡小琪	100050 北京, 中国疾病预防控制中心营养与食品安全所	huxiaoqee@163.com

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中文摘要:

目的分析儿童维生素D的营养状况及其与体成分的关系。方法选取北京市怀柔区(北纬40.3。)7一ll岁学龄儿童381名，于2008年3月采集静脉血并采用酶联免疫吸附试验(ELISA，英国IDS公司)测定血清中25一羟维生素D[25(OH)D]的浓度，双能x线吸收仪(DEXA，美国Norland公司)测定前臂及全身的体成分，分析维生素D与体成分的相关性。结果研究对象血清25(OH)D的平均浓度为(44.4±12.5)nmol/L，维生素D缺乏和不足率[血清25(OH)D≤50mol/L]达68.5％。男生血清25(OH)D浓(46.3±13.3)nmol/L高于女生(42.0±11.1)nmoFL，差异有统计学意义(t=3.38，P<0.01)。血清25(OH)D浓度与前臂近端、远端、全身及分部位中四肢的瘦体重呈正相关(r=0.13—0.19，P<0.05)，与前臂近端、远端的体脂百分比呈负相关(r=一0.14，P<0.05；r=一0.11，P<0.05)，均有统计学意义。调整年龄、性别、身高、体重等混杂因素后，与前臂近端、全身分部位中双下肢的瘦体重相关性仍有统计学意义(r=O.12～0.14，P<0.05)。血清25(OH)D浓度与各部位体脂的相关性均无统计学意义。结论维牛素D缺乏在北京市郊区儿童中较为普遍，而维生素D营养状况对体成分。尤其对瘦体重有促进作用。

英文摘要:

Objective To analyze vitamin D concentration and its association谢th body composition of children in Huakou district of Beijing，to provide evidence for evaluation and improvement of nutritional status of vitamin D in children.Methods Totally.38 l children aged 7一ll years were recruited in Huairou district ofBei_iing(40.30N).Samples ofovernight fasting venous blood(drawn between 0630 and 0900)were obtained in late March.Serum 25.hydroxyvitamin D[25(0H)D] concentrationwas determinedby ELlSAkits(IDS Ltd，UK).Body compositionindices of the whole body。the distal and proximal forearm were measured using dual—energy X—ray absorptiometry(DEXA，Norland，USA).Results The average serum 25(OH)D concentration of all subjects was(44.4±l 2.5)nlnoI/L.The percentage of vitamin D insufficient[serum.25(OH)D≤ 50 nmol/Lj reached ashighas 68.5％(261 people).The25(OH)D concentrationofboys(46.3 nmoI/L± 13.3 m01/L)was significantly higher than that of girls(42.0 nmol/L±11.1 111110I/L)，(f=3.38，P< 0.0 1).Between the serum 25(OH)D concentration and Ican body mass of proximal forearm.distal forearm，whole body，and four limbs，significant positive correlations r=0.13—0.19，P<0.05)were observed.After age，gender，height and weight were under controlled for，correlations between the serum 25(OH)D concentration and lcan bodv mass at proximal forearm。and the two lower limbs still existed(r=O.12—0.14，P<0.05).ne serum 25(OH)D concentration.the percentage ofbodv fat at proximal forearm，and distal forearm were negatively correlated(r=_o.14，P<0.05：r=-0.1l，P<0.05).Howevgr，after adjusting for confounding effects。this correlation disappeared.No significant correl|ation between the serum 25(OH)D concentration and body fat was observed at any position.Conclusion Vitarnin D deficiency Was common in children of suburb area of Beijing.Vitamin D status Was positively associated with the lean body mass.

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