文章摘要
陈梦施,杨华林,陈艳芳,谭红专,白丽琼,张艳辉,刘军,李桂平.湖南省HIV/AIDS人群结核发病影响因素的巢式病例对照研究[J].中华流行病学杂志,2010,31(2):151-154
湖南省HIV/AIDS人群结核发病影响因素的巢式病例对照研究
A nested case·control study on the influencing factors of tuberculosis among people living withHIV/AIDS in Hunan province
收稿日期:2009-08-03  出版日期:2014-09-12
DOI:
中文关键词: 艾滋病  结核  巢式病例对照研究  影响因素
英文关键词: Acquired immunedeficiency syndrome  Tuberculosis  Nested case-control study  Influencing factors
基金项目:全球基金中国结核病实施性研究(07-062)
作者单位E-mail
陈梦施 长沙, 中南大学公共卫生学院流行病学教研室, 410078  
杨华林 湖南省结核病防治所  
陈艳芳 岳阳楼区疾病预防控制中心  
谭红专 长沙, 中南大学公共卫生学院流行病学教研室, 410078 tanhz99@qq.com 
白丽琼 湖南省结核病防治所  
张艳辉 长沙, 中南大学公共卫生学院流行病学教研室, 410078  
刘军 衡阳市疾病预防控制中心  
李桂平 祁东县疾病预防控制中心  
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中文摘要:
      目的探讨HIV/AIDS人群发生结核病的危险因素。方法采用1:2匹配的巢式病例对照研究方法分析HW/AIDS人群发生结核的危险因素。结果对1018例未患结核的HIV/AIDS人群随访观察1年,累计观察736.75人年,共检查出结核病患者62例,HIV/AIDS人群结核病发病密度为8.42A/100人年(62人/736.75人年)。文化程度(OR=O.483)、卡介苗接种史(OR=0.561)、CD。+T淋巴细胞数(OR=O.356)、无业(OR----1.976)、单身(OR=2.646)和吸烟(OR=2.215)等因素与HIV/AIDS人群发生结核病有关。结论文化程度高、有卡介苗接种史和CD4+T淋巴细胞数高是HIV/AIDS人群患结核病的保护因素;无业、单身和吸烟是HIV/AIDS人群患结核病的危险因素。
英文摘要:
      Objective To determine the risk factors related to tuberculosis infection among people living with HIV/AIDS and to develop strategies for preventing the CO-infection.Methods A 1:2matched nested case.control study was can-/ed out to analyze the influencing factors of tuberculosis among people living with HIV/AIDS.Results 1018 people living with HIV/AIDS were followed up for one year with a total number of 736.75 person.years。among them 62 tuberculosis cases were diagnosed.The incidence density of tuberculosis among people living with HIV/AIDS Was 8.42persons per 100 person-years.Factors as education level(0R=0.483)。vaccination history ofBacille Calmette Guerin(OR=O.561)。CD4count T-lymphocyte(OR=O.356),unemployment(OR=1.976),living alone(0R=2.646)。and smoking(OR=2.215)were significantly related to the prevalence of tuberculosis among people living with HIv/AIDS.Conclusion High education level,with vaccination history of Bacille CalmeRe Guerin and high level of CD4+T-lymphocyte count were protective factors while being unemployed,living alone,and smoking habit were risk factors related to the prevalence of tuberculosis among people living with HJV/AIDS.
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