| 裴迎新,李兴旺,张智清,施国庆,郭建强,申涛,曾光.59例经网络征集的“自疑HIV感染者”流行病学特征与临床表现的分析[J].中华流行病学杂志,2010,31(12):1379-1382 |
| 59例经网络征集的“自疑HIV感染者”流行病学特征与临床表现的分析 |
| Epidemiologic and clinical characteristics of 59 persons suspecting of being infected by the HⅣ virus despite having repeated negative laboratory findings |
| 收稿日期: 出版日期:2014-09-18 |
| DOI：10.3760/cma.j.issn.0254-6450.2010.12.012 |
| 中文关键词: 艾滋病 自疑HIV感染 网络 |
| 英文关键词: Acquired immunodeficiency syndrome Self-suspected HIV infection Intemet |
| 基金项目:中国医药卫生事业发展基金会项目；中国疾病预防控制中心性病艾滋病预防控制中心基金(42) |
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| 中文摘要: |
| 目的了解网络征集的59例"自疑HIV感染者"流行病学特征和临床表现.方法"自疑HIV感染者"定义为网络聊天室中自诉具有至少3项类似艾滋病症状者:持续低热、皮疹、淋巴结肿大、乏力、腹泻、体重下降或CD4+T淋巴细胞计数低于正常.通过网络问卷调查,在88例报名者中选择59例做志愿临床检查与实验室检测.结果59例"自疑HIV感染者"来自22个省市),男性54例(91.5%),平均年龄34岁(22—53岁).84.7%"自疑HIV感染者"在出现自述"症状"前有过高危性行为."暴露"至"症状出现"之间的时间间隔中位数为15 d(1~365 d).59例"自疑HIV感染者"的HIV抗体、梅毒抗体及嗜异种性小鼠白血病病毒相关病毒(XMRV)检测均为阴性;l例丙型肝炎抗体检测阳性,CIM+T淋巴细胞计数算术均数为707个/"l.59例"自疑HIV感染者"中,有57例(96.6%)参加系统临床检查,40例无明显器质性病变.结论未发现59例"自疑感染者"存在HW感染证据,也未发现有可以解释其症状的传染性疾病存在. |
| 英文摘要: |
| Objective To describe the epidernioiogic characteristics and clinicM manifestations of 59 persons recruited via an internet chat group who complained of AIDS—like symptoms．50 as to formulate effective intervention strategies and measures．Methods Case was defined as onset of any three of the following self-reported AIDS．1iIce symptoms in a member of relevant“internet chat groups”：persistent low grade fever，rash，swollen lymph node，fatigue，diarrhea，weight loss and lOW C134+T count．We administered all intemet-based quesfionnmre，and invited 59 of the 88 case． persons for voluntary physical examination and laboratory testing．Results the 59 Case—persons came from 22 provinces；54(91．5％)were men；the median age was 34(range：22-53)years；84．7％ofthem had high—risk sexual behaviors before the onset of self-reported symptoms．The mediall time interval from exposure to onset was l 5 d(range：l一365 d)．Blood specimens for all the 59 case．persons were tested negative for HIV and syphilis antibodies，There Was also n0 evidence of Xenotropic murilie leukemia virus—related virus infection．One case．person was tested positive for hepatitis C virus antibody．The average CD4'T lymphocyte count Was 707/!a1．Of the 59 case·persons， 57(96．6％)sought medical care from multiple providers；40 were diagnosed to have no physical disorders．conclusion None of the 59 case．persons had any evidence of infection with HIV or any other infectious agents that could explain their self-reported symptoms． |
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