文章摘要
孙冬玲,何耀.代谢综合征的相关流行病学研究进展——是抛弃还是进一步探索[J].中华流行病学杂志,2011,32(8):746-750
代谢综合征的相关流行病学研究进展——是抛弃还是进一步探索
A review of metabolic syndrome:to give up or carry on further research
收稿日期:2011-06-02  出版日期:2014-09-17
DOI:
中文关键词: 代谢综合征;流行病学
英文关键词: Metabolic syndrome;Epidemiology
基金项目:国家自然科学基金(81072355);首都医学发展科研基金(2007-2039)
作者单位E-mail
孙冬玲 100853 北京,解放军总医院老年医学研究所  
何耀 100853 北京,解放军总医院老年医学研究所 yhe301@sina.com 
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中文摘要:
      代谢综合征(MS)表现为一组代谢危险因素的聚集状态,包括糖代谢异常、血脂异常、血压升高、腹型肥胖、低度炎症和凝血溶血功能异常等,MS与动脉粥样硬化性心血管疾病(CVD)和2型糖尿病(T2DM)的发病和死亡风险升高密切相关。目前一般认为MS的病因可能为肥胖和胰岛素抵抗(IR),更详细的发病机制仍不清楚。
英文摘要:
      explore the factors affecting blood level of elderly hypertensive patients,using a multilevel analysis model.Methods 927 elderly hypertensive patients from 23 communities were studied,through a multi-stage random sampling method.The influencing factors on systolic blood pressure (SBP) and diastolic blood pressure (DBP) were analyzed through a two-level linear multilevel model,respectively.Results The average blood pressure of subjects appeared as:SBP (139.2±11.7) mm Hg ( 1 mm Hg=0.133 kPa),DBP (85.6±8.6) mm Hg.Ratio of physician versus patients was the factor affecting blood level of subjects from the community level.SBP and DBP of the subjects from the higher physician/patient ratio communities were 3.86 mm Hg and 2.51 mm Hg,lower than the subjects in the lower ratio communities,after controlling the other related factors.Age,gender,overweight/obesity were the individual risk factors of hypertension,while factors as regularl medicine taking,reducing salt intake and related self-efficacy to manage disease could reduce the blood pressure.Reducing salt intake could lower the SBP for 2.44 mm Hg and DBP for 2.03 mm Hg,after controlling the other factors.Conclusion Multilevel analysis model could effectively analyze the hierarchically structured data while both factors from the community and individual levels could affect the blood level among elderly patients with hypertension.
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