| 张高辉,马吉祥,郭晓雷,董静,陈希,张吉玉,苏军英,唐俊利,徐爱强.低钠富钾替代盐对农村社区人群血压影响的现场观察[J].中华流行病学杂志,2011,32(9):859-863 |
| 低钠富钾替代盐对农村社区人群血压影响的现场观察 |
| Field observation on the effect of Iow-sodium and high-potassium salt substitute on blood pressure in ruralcommunity-based population in China |
| 收稿日期:2011-03-31 出版日期:2014-09-11 |
| DOI： |
| 中文关键词: 高血压 低钠富钾替代盐 社区人群 干预效果 |
| 英文关键词: pertension Low-sodium and high-potassium salt substitute Community population Intervention effect |
| 基金项目:卢森堡-世界卫生组织-山东省农村卫生人员培训及慢病控制项目(2007--2010) |
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| 中文摘要: |
| 目的评价市售低钠富钾替代盐对农村社区居民血压的影响效果。方法采用流行病学类实验设计，在山东省莱芜市2个农村社区。经过血压筛查，将411名30-60岁的研究对象分为高血压组和非高血压组，两组均以家庭为单位给予3个月的低钠富钾替代盐替换普通食盐进行干预.定期观察血压及其24 h尿钠的变化。结果用低钠富钾替代盐干预1个月时高血压组和非高血压组人群血压开始呈下降趋势，3个月后评估时高血压组收缩压(SBP)平均下降7.4 mmHg(1mmHg=0.133kPa；t=10.096。P=0.000)，舒张压(DBP)下降3.8mmHg(t=8.017，P=0.000)；非高血压组SBP平均下降1.2 mmHg(t=2.507。P=0.007).DBP下降1.0mmHg(t=2.987，P=0.002)。干预3个月后评估时高血压组24 h尿钠平均下降15.5 mmol(t=1.803。p=0.037).尿钾上升4.2mmol(t’=2.132，P=0.018)，钠钾比下降1.2(t----2.786，P=0.003)；非高血压
组24 h尿钠平均下降1.7retool(t=0.211。P=0.417)，尿钾上升3.7mmol(t’=2.207，P=0.015)，钠钾比值下降O.7(‘=1.818。P=O.036)。结论低钠富钾替代盐能有效降低人群血压水平，且人群依从性较好，是-种有效的非药物预防控制高血压方法。 |
| 英文摘要: |
| Objective To investigatet he effect of commercial low-sodium and high-
potassium salt substitutes on blood pressure in the rural community-based population in China.Methods We conducted a quasi-experiment on 4ll
adults,who were 30 to 60 years of age.in 2 rural communities from Laiwu city in Shandong province of China on data from blood pressure screening.The subjects were divided into 2 groups：high blood pressure(HBP)and non-HBP(NHBP).Both groups
and their family members took a low-sodium and high.potassium salt substitute for 3 months to replace the normal salt in their bodies.Blood pressure(BP)and 24一hour urinary sodium and potassium were measured regularly in the 2 groups.Resuits
There was a continuously decreasing trend for BP at the end of the first month.me
months lateT.the mean BP decreased by 7.4 mmHg(1 mmHg=0.133kPa。t=10.096.P=O.000)for SBP and 3.8 mmHg(I=8.017,P=O.000)for DBP in the HBP group.when compared to a 1.2 mm
Hg(t=2.507。P=0.007)decrease on SBP and 1.0 mmHg(t=2.987，P=0.002)on DBP in the NHBP group.The mean urinarys odium had a decrease of 15.5 retool／24 h(t=1.803.P=0.037).but the urinary potassium increased by 4.2retool／
24h(t’=2.132.P=0.018).The result of urinary sodium appepared to be as
foIiows：potassium ratio (Na+／K+)decreased by 1.2(t---=-2.786.P----0.003)in the HBP group.HowevJat‘.in NHBP group.the mean urinary sodium decreased
by 1.7 mm01／24 h(I=O.2ll。P--0.417)and urinary potassium increased by
3.7 mmol/24h(t’=2.207，P=O.015)，together with the decrease ofNa+／K+by O.7(f=1.818,P=0.036).Conclnsion Results from our stuay clearlyd emonstrated that the intake of low.sodium and high-potassium salts
ubstitute could effectively reduce the BP with good compliance among adults in the rural community-based population in China.This was all effective but non-medical method to prevent and control the high blood pressure. |
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