文章摘要
陈建国,陈万青,张思维,郑荣寿,朱健,张永辉.中国2003--2007年肝癌发病率与死亡率分析[J].中华流行病学杂志,2012,33(6):547-553
中国2003--2007年肝癌发病率与死亡率分析
Incidence and mortality of Hver cancer in China: an analysis on data from the National Registration System between 2003 and 2007
收稿日期:2012-02-18  出版日期:2014-09-09
DOI:
中文关键词: 肿瘤  发病率  死亡率  癌症登记  流行病学
英文关键词: Liver neoplasm  Incidence  Mortality  Cancer registration  Epidemiology
基金项目:财政部、卫生部公共卫生专项肿瘤随访登记项目(财社[2008]293号、财社[2009]193号、财社[2010]90号)
作者单位E-mail
陈建国 南通大学肿瘤医院肿瘤研究所 226361
启东肝癌防治研究所 
chenjg@vip.sina.com 
陈万青 中国医学科学院肿瘤研究所肿瘤医院全国肿瘤登记中心 chenwq@eicams.ac.cn 
张思维 中国医学科学院肿瘤研究所肿瘤医院全国肿瘤登记中心  
郑荣寿 中国医学科学院肿瘤研究所肿瘤医院全国肿瘤登记中心  
朱健 启东肝癌防治研究所  
张永辉 启东肝癌防治研究所  
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中文摘要:
      目的 根据癌症登记报告资料, 描述和探讨2003-2007年中国肝癌发病和死亡的特征与趋势.方法 采用中国32个癌症登记处2003-2007年肝癌发病与死亡登记年报资料, 计算与分析肝癌的发病(死亡)率、中国人口标化率及世界人口标化率;并作年龄别、性别和城乡间发病(死亡)率差异及国际发病(死亡)率的比较分析.结果 2003-2007年中国32个癌症登记处观察总数为255 430909人年, 其中城市197 651 428人年, 农村57 779481人年.共登记报告肝癌发病68 146例, 占全部癌症发病病例的10.03%(居第2位).年均发病率为26.68/10万(男性39.42/10万, 女性13.63/10万), 中国和世界人口标化率分别为14.54/10万和20.93/10万;登记报告肝癌死亡63928例, 占全部癌症死亡病例的14.56%(居第2位).年均死亡率为25.03/10万(男性36.41/10万, 女性13.37/10万), 中国和世界人口标化率分别为13.29/10万和17.45/10万.肝癌发病率和死亡率性别比分别为2.89:1和2.72:1.城市和农村地区肝癌发病率分别为23.91/10万和36.15/10万, 死亡率分别为22.39/10万和34.05/10万.肝癌发病和死亡有较大的地区差异:城市发病率10.15/10万至33.85/10万, 而农村为11.83/10万至78.59/10万;城市死亡率在13.99/10万至28.45/10万, 农村为11.02/10万至71.99/10万.在同期全球184个国家或地区中, 中国肝癌发病率水平男性居第5位, 女性居第6位;死亡率水平男性居第2位, 女性居第5位.结论 肝癌是中国目前仅次于肺癌的最主要恶性肿瘤, 每年发病和死亡人数分别约在36万和35万, 并有继续增高的趋势.应当加强全国性的肝癌监测和防治.
英文摘要:
      Objective To describe and analyze the characteristics and trend of liver cancer, through data gathered from the Cancer Registry System, in China.Methods Annual registration data on cancer incidents and deaths of 2003-2007, from 32 cancer registries were employed.Crude rates of incidence and mortality, and age-standardized rates by the China population (ASRc) and the world population (ASRw) were calculated.Incidence and mortality rates by age, gender, and by area (urban or rural) were analyzed, and comparison was made internationally, based upon data from the GLOBOCAN 2008.Results The total person-years of 2003-2007 observed from the 32 cancer registries were 255 430 909, in which 197 651 428 from the urban areas, and 57 779 481 from the rural areas.A total of 68 146 incident cases with liver cancer were reported, which accounted for 10.03%(ranked second) of all the registered cases with cancers, with the average annual incidence as 26.68per 100 000 (39.42 in males, 13.63 in females).ASRc and ASRw were 13.29 per 100 000 and 17.45per 100 000, respectively.Sex ratios for incidence and mortality were 2.89:1 and 2.72:1, respectively.Incidence rates were 23.91 per 100 000 in urban areas, and 36.15 per 100 000 in rural areas.For mortality rates, they were 22.39 per 100 000 m urban areas and 34.05 per 100 000 in rural areas, respectively.Relative greater differences could be seen amongst these registries.The incidence rates were 10.15-33.85 per 100 000 in the urban areas, and 11.83-78.59 per 100 000 in the rural areas.For mortality rates, they were 13.99-28.45 per 100 000 in urban areas, and 11.02-71.99 per 100 000 in rural areas.According to data from the 184 cancer registries through GLOBOCAN 2008, liver cancer incidence in China was ranked the 5th in males, and 6th in females while mortality was ranked 2nd in males, and 5th in females.Conclusion Liver cancer had been the second most leading malignancy, following lung cancer, with annual incidents and death cases around 360 000 and 350 000, respectively and the figures seemed to be increasing.Nationwide monitoring and research programs on liver cancer should be emphasized.
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