| 常亮,常靖,冯石献,周刚.癫痫综合干预成本-效用分析[J].中华流行病学杂志,2012,33(9):912-916 |
| 癫痫综合干预成本-效用分析 |
| Cost-unitty analysis of comprehensive intervention on epilepsy |
| 收稿日期:2012-02-17 出版日期:2014-09-17 |
| DOI：10.3760/cma.j.issn.0254-6450.2012.09.008 |
| 中文关键词: 癫痫 伤残挑整生命年 质量调整生命年 成本-效用 |
| 英文关键词: Epilepsy Disability adjusted life years Quality-adjusted life years Cost-utility |
| 基金项目:河南省医学重点学科、临床特色专科学术技术带头人培养训划项目(201018-66)；卫生部中央补助地方农村地区癫痫防治管理项目(财社[2006]126号) |
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| 中文摘要: |
| 目的 对癫痫综合十预的效果进行卫生经济学评价。方法 在河南省9个项目示范点对874例癫痫患者进行调查。以农村癫痫防治管理项目研究为依托，计算癫痫综合干预的成本，以伤残调整生命年(DALY)和质蛙调整生命年(QALY)为效用指标进行成本效用分析。结果874侧患者中，综合干预组(422例)人均损失8.58个DALY，获得27.95个QALY，获得1个QALY需付出的成本为2454.10元，挽救1个DALY需付出7995.40元；相对于无干预对照组(452例)，综合干预组获得QALY所需成本碱少，挽救1个DALY少投入21 735.10元。结论 癫痫对社会、家庭、患者本人造成严重的绎济损害，综合性十惯可以更好地降低癫痫患者的疾病经济负担，具有较高的成本一效用收益，值得推广。 |
| 英文摘要: |
| Objective To discuss the cost-utility regarding the effect of comprehensive intervention program on epilepsy．Methods 874 cases with epilepsy were investigated in 9 pilot sites in Henan province. Cost of epilepsy comprehensive intervention was calculated based on the research projects of epilepsy prevention and management of rural areas．Disabiliry-adjusted life year (DALY) and quality adjusted life year (QALY) were used as ufility index for cost-utility analysis．Results Of the 874 cases．8.58 DALY was lost and 27.95 QALY was obtained per capita in the intervention group (422 cases). The costs per QALY and DALY obtained were 2454.10 and 7995.40 Yuan, respectively．Relative to the non-intervention control group (452 cases), the costs for QALY obtained by the intervention group had reduced. The investment would reduce 2l 735.10 Yuan when each additional DALY was saved. Conelnsion Epilepsy caused serious economic burden to the society．families and the patients themselves. Comprehensive intervention program could reduce the economic burden of the disease thus yielding high cost-benefit. This program WBS deserved to be promoted. |
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