程晓青,庞琳,曹晓斌,王常合,罗巍,张波,王华,李荣健,柔克明,吴尊友.云南和广西地区部分美沙酮门诊HIV感染者抗病毒治疗现状及其影响因素[J].中华流行病学杂志,2013,34(8):792-795 |
云南和广西地区部分美沙酮门诊HIV感染者抗病毒治疗现状及其影响因素 |
Current situation related to antiretroviral therapy and related influential factors on HIV infected injection drug users in the methadone maintenance treatment clinics |
收稿日期:2013-03-10 出版日期:2014-09-03 |
DOI: |
中文关键词: 美沙酮维持治疗|抗病毒治疗|影响因素|吸毒人群 |
英文关键词: Methadone maintenance treatment|Antiretroviral therapy|Influential factors|Drug users |
基金项目:国家科技重大专项(2012ZXl0001007—002);美国国立卫生研究院(NIH)福格底国际中心(FIC)"中国艾滋病和结核病多学科培训项目"(2U2RTW006918-07) |
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中文摘要: |
目的 了解参加美沙酮维持治疗(MMT)的HIV感染者接受抗病毒治疗(ART)现况及影响因素.方法 在云南和广西地区6个MMT门诊中选取291名HIV感染者,调查内容包括研究对象-般人口学特征、海洛因滥用、HIV感染、MMT及ART接受情况.结果 研究对象中共有男性217人(74.6%),女性74人(25.4%),平均年龄(38.4±5.9)岁,以高中以下文化程度、已婚、无业人员为主.单因素分析发现,有固定工作、独自居住、自报过去1个月饮酒、家人对MMT不支持/不了解/无所谓、自报过去1个月未能每天进行MMT、未享受MMT门诊优惠政策、未将HIV感染告知他人、自觉身体状况较好或-般、过去6个月从未和家人谈论ART话题、不知道家人对ART态度以及缺乏对ART效果的正确认识是影响MMT门诊HIV感染者接受ART的主要因素;多因素logistic回归分析发现,独自居住、未将HIV感染告知他人、自觉身体状况好、过去6个月从未和家人谈论ART相关话题和不知道家人对ART态度是影响MMT门诊HIV感染者接受ART的5个主要因素.结论 重视MMT对ART的积极作用,加强对MMT门诊HIV感染者及其家属ART知识宣传,积极促进HIV感染者获得家庭支持,有可能促进MMT门诊吸毒HIV感染者接受ART. |
英文摘要: |
Objective To find out the current coverage of antiretroviral therapy (ART) among HIV positive subjects and to identify the major influential factors associated with the participation in ART among them.Methods 291 HIV positive subjects from 6 methadone maintenance treatment (MMT) clinics in Guangxi and Yunnan province were surveyed by questionnaires.Results 217 males (74.6%) and 74 females (25.4%) were under investigation,with the average age of 38.4 ± 5.9.Most of them received less than senior high school education,married and unemployed.Results from the single factor logistic regression analysis showed that:working status,living alone,self-reported history of drinking alcohol in the last month,negative attitude towards MMT among family members,poor self-reported compliance to MMT in the last month,lack of incentives in the MMT clinics,reluctance on disclosure of their own HIV status,good self-perception on their health status,lack of communication on ART related topics among family members in the last 6 months,lack of correct attitude and knowledge on ART etc.appeared as the main factors that influencing the participation in ART program among the patients.Data from the multivariate logistic regression analysis showed that factors as:living alone,unwilling to tell others about the status of HIV infection,poor self-perception on HIV infection,lack of discussion of ART related topics within family members in the last 6 months and poor awareness towards ART among the family members etc.,were associated with the low participation rate of ART.Conclusion Strengthening the publicity and education programs on HIV positive patients and their family members at the MMT clinics seemed to be effective in extending the ART coverage.Attention should also be paid to increase the family support to the patients. |
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