| 程锦泉,马汉武,谢旭,路滟,张艳彪,董书贤,王廷哲,刘益民,凌文华,郝元涛.深圳市常住人口乙型肝炎血清流行病学调查[J].中华流行病学杂志,2013,34(12):1179-1182 |
| 深圳市常住人口乙型肝炎血清流行病学调查 |
| Sero-epidemiological investigation on hepatitis B among permanent residents in Shenzhen area |
| 收稿日期:2013-07-12 出版日期:2014-10-16 |
| DOI：10.3760/cmaj.issn.0254-6450.2013.012.006 |
| 中文关键词: 乙型肝炎 流行病学 |
| 英文关键词: Hepatitis B Epidemiology |
| 基金项目:国家“十一五”科技重大专项 (2009ZXl0001—018) |
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| 中文摘要: |
| 目的调查深圳市常住人13 HBV感染情况及流行特征。方法2010年采用多阶段分层随机抽样方法对深圳市罗湖区和宝安区1～59岁常住居民进行问卷调查,并采集静脉血,用ELISA检测乙型肝炎(乙肝)病毒表面抗原(HBsAg)和乙肝病毒表面抗体(抗-HBs)。结果3771人中,HBsAg阳性252例,标化阳性率为9.73%；抗一HBs阳性2712例,标化阳性率为72.83%。HBsAg阳性率随年龄增长呈升高趋势(P<0.05)；深圳市户籍与非深圳市户籍居民HBsAg阳性率差异无统计学意义(P>0.05),但深圳市户籍人口抗一HBs阳性率(78.32%)高于非深圳市户籍人群(66.03%),差异有统计学意义(X2=41.613,P<0.001)；HBsAg阳性率在不同职业人群中差异较大,其中农民最高,达24.13%,抗-HBs阳性率中医护人员最高(89.10%)；初中文化程度人群HBsAg阳性率最高(12.76%),大专及以上文化程度人群抗-HBs阳性率最高,平均为81.00%,而初中水平人群抗-HBs阳性率最低,仅为62.45%；出生地为广东、深圳地区的调查人群HBsAg阳性率均超过10%,抗一HBs阳性率以深圳和广东地区出生人群最高,分别为74。48%和76.47%。结论深圳市乙肝感染低于广东省,但高于全国平均水平。 |
| 英文摘要: |
| 0bjective To understand the infection status and epidemiological features ofHBV in permanent residents of Shenzhen city.Methods A multi.stage stratified random samplingmethod was performed for questionnaire survey to permanently.registered residents of 1-59 years oldin Luohu and Baoan district of Shenzhen in 20 1 0，and blood samples of the subjects were collected.Hepatitis B virus-related surface antigen(I-IBsAg)and hepatitis B virus surface antibody(anti-HBs)were detected with ELISA.ResultsP>0.05).The prevalence of HBsAg was reduced with increasingage.The differences of the prevalence of HBsAg between Shenzhen permanent registered andnon-permanent registered population were not significant，but the prevalence of anti-HBs inPermanent registered residents(78.32%)was higherthan in non permanent(66.03%.X2=41.613.P<0.001).The prevalence of HBsAg was significantly different in various occupational and educational1evels.Peasants had me highest prevalence(24.13%)and medical workers had the highestprevalence of anti·HBs(89.10%).People with juniorhigh school education had the high estprevalence of HBsAg(12.76%)and the lowest of anti.HBS(62.45%).Population with high.1eveleducation had the highest prevalence of anti.HBs(8 1.00%average).The prevalence of HBsAg wasover 10%in people who were bom in Shenzhen and Guangdong province.and the anti.HBs was thehighest in Shenzhen population with the prevalence as 74.48%and 76.47%，respectively.Conclusion In the Shenzhen resident population.the overall prevalence of HBV was lower than theaverage level of Guangdong province.but higher than the national wide. |
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