| 张琳,成宏伟,周余春,袁子宇,陈甜甜,陈兴栋,吕明.江苏省泰兴地区食管鳞癌发病与社会经济状况的关联研究[J].中华流行病学杂志,2014,35(2):147-150 |
| 江苏省泰兴地区食管鳞癌发病与社会经济状况的关联研究 |
| Association between socioeconomic status and esophageal squamous cell carcinoma in the population of Taixing area, Jiangsu province |
| 收稿日期:2013-10-18 出版日期:2014-09-17 |
| DOI：10.3760/cma.j.issn.0254-6450.2014.02.010 |
| 中文关键词: 食管鳞癌 社会经济状况 病例对照研究 主成分分析 |
| 英文关键词: Esophageal squamous cell carcinoma Socioeconomic status Case-control study Principal component analysis |
| 基金项目:国家自然科学基金（81072358，81273151）；江苏省科技支撑计划（BE2011763） |
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| 中文摘要: |
| 目的 分析江苏省泰兴地区人群社会经济状况与食管鳞癌发病的关系。方法 采用病例对照研究，收集人口学资料、社会经济状况指标及可能的危险因素，使用主成分分析法计算财富得分，利用非条件logistic回归方法调整混杂因素，计算多种社会经济状况指标与食管鳞癌发病的OR值及其95％CI。结果 多因素分析显示，教育程度为高中及以上（OR=0．66，95％CI：0．46～0．96）、人均居住面积≥67 m2（OR=0．71，95％CI：O．54～0．94）、饮用自来水超过5年（OR=0．76，95％CI：0．59～0．98）以及财富得分>0．93（OR=0．63，95％CI：0．48～0．83）食管鳞癌发病危险低。从事商业、服务业人员与从事农、林、牧、渔、水利业生产者相比，发生食管鳞癌的危险性低（OR=0．65，95％CI：0．43～0．97）。结论 社会经济状况与江苏省泰兴地区食管鳞癌发病为负性关联，其相关机制有待进一步研究。 |
| 英文摘要: |
| Objective To study the relationship between socioeconomic status (SES) and esophageal squamous cell carcinoma(ESCC ) in Taixing city, Jiangsu province. Methods A population- based case-control study was carried out to collect data including demography, socioeconomic status indicators and possible risk factors. Unconditional logistic regression was used to compare different SES indicators and composite wealth scores constructed between cases and controls,using the principal component analysis methodology. Results Factors as: having received high school or higher education (OR=0.66, 95%CI: 0.46-0.96)，living space over 67 m2 per-capita (OR=0.71，95% CI: 0.54-0.94 )，drinking tap water longer than 5 years (OR=0.76, 95% CI: 0.59-0.98) and wealth score >0.93(0R-0.63，95%Cl: 0.48-0.83 ) were associated with increased risk of ESCC. Compared to those worked in farming, forestry, animal husbandry, fishery and water conservancy, the individuals who worked in business-service industry were at lower risk of ESCC ( OR=0.65，95%Cl: 0.43-0.97 ). Conclusion An inverse association of low SES and ESCC were found in Taixing people that called for further explanation. |
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