| 王曼,张丽杰,夏生林,吴海东,张瑞红,范木耿,汪涛.洋葱伯克霍尔德菌污染B超耦合剂致剖宫产术后切口感染的调查[J].中华流行病学杂志,2014,35(5):566-568 |
| 洋葱伯克霍尔德菌污染B超耦合剂致剖宫产术后切口感染的调查 |
| An investigation on surgical-site infection among post cesarean section patients with Burkholderia cepacia contaminated ultrasonic couplant |
| 收稿日期:2013-12-13 出版日期:2014-09-17 |
| DOI：10.3760/cma.j.issn.0254-6450.2014.05.021 |
| 中文关键词: 手术切口感染 洋葱伯克霍尔德菌 超声波耦合剂 |
| 英文关键词: Surgical-sites infection Burkholderia cepacia Ultrasonic couplant |
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| 中文摘要: |
| 目的 查明2013年5月中山市某医院剖宫产术后切口感染罹患率异常增高的原因，并提出控制措施。方法 调查该医院2011年1月至2013年6月剖宫产术后切口感染病例资料，并访谈剖宫产手术流程；针对2013年5月切口感染病例，开展1∶2 病例对照研究；采集感染切口分泌物和环境标本进行细菌培养检测，阳性菌株利用脉冲场凝胶电泳（PFGE）进行分子分型。 结果 2013 年 5 月该医院有 4 例剖宫产术后切口感染患者，罹患率为 10.3%（4/39）。手术至术后切口感染间隔2～3 d；入院至手术间隔2～9 h（M＝7.2 h），其时间短于未发生切口感染患者（M＝20.8 h）（Z＝5.50，P＝0.03）。其中2例分别于术前1.4、8.4 h做过B超检查，另2例有术前2 h持续胎心音监护史，4例患者手术区域皮肤均接触B超耦合剂，且未彻底清洁。切口感染患者术前10 h内进行B 超检测或胎心音监护的比例高于切口未感染患者（χ2＝5.19，P＝0.01）。于1例患者切口分泌物、2 份 B 超探头涂抹拭子及在使用和未开封的 B 超耦合剂（同批号）中均检测出洋葱伯克霍尔德菌（BC），PFGE分型显示5株菌的同源性为100%。结论 患者剖宫产术前手术区域皮肤接触BC污染的B超耦合剂，且未彻底消毒，导致切口感染暴发。 |
| 英文摘要: |
| Objective In May 2013，an abnormal increase of surgical-site infection among post cesarean section patients was reported at one hospital in Zhongshan. An investigation was conducted to identify the risk factors and related control measures. Methods All the reported surgical-site infection records among post cesarean section patients were checked. A review of cesarean section schedules of health workers was also performed. An 1∶2 case-control study was conducted among surgical-site infection cases in May 2013. Microbiologic cultures were performed on 2 surgical site secretion samples and 12 samples from the environment. All the positive isolates were molecular typed by pulsed field gel electrophoresis（PFGE）. Results In May 2013，4 post cesarean section patients who developed surgical-site infection symptom at one hospital in Zhongshan were reported，with an attack rate as 10.3%（4/39）. The emergence time of symptom was 2-3 days after operation. All of the 4 cases underwent an emergency operation. The median time interval for cases from admission to operation was 7.2 hours（ranged from 2 to 9 hours），lower than that seen in the controls，with a median time of 20.8 hours（Z＝5.50，P＝0.03）. Two of the 4 cases took type-Bultrasonic inspection 1.4 h and 8.4 h before the operation，and the other two cases took continuous fetal heart monitoring 2 hours before the operation. Skin of the operation area on the 4 cases had been exposed to ultrasonic couplant，without a thorough clean. The proportion of type-B ultrasonic inspection or continuous fetal heart monitoring was much higher in cases than in controls（χ2＝5.19，P＝0.01）. Burkholderia cepacia（BC）isolates were discovered from：one surgical site secretion type-B ultrasonic probe samples，one ultrasonic couplant in use and one ultrasonic couplant unopened. All the isolates were identified as 100% identical by PFGE. Conclusion The skin of operation area of cesarean section patients had been exposed to BC contaminated ultrasonic couplant without thorough cleaning，which seemed to be related to the outbreak of surgical-site infection，in our case. |
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