文章摘要
李晓宁,罗雷,肖新才,景钦隆,魏跃红,李意兰,曹庆,杨智聪,许雅.广州市登革热散发和暴发布雷图指数临界值分析[J].中华流行病学杂志,2014,35(7):821-824
广州市登革热散发和暴发布雷图指数临界值分析
Using Breteau Index to analyze the nature of sporadic and outbreak cases of Dengue fever
收稿日期:2014-01-12  出版日期:2014-09-01
DOI:10.3760/cma.j.issn.0254-6450.2014.07.015
中文关键词: 登革热  布雷图指数  临界值
英文关键词: Dengue fever  Breteau index  Threshold
基金项目:国家自然科学基金(81273139);广东省自然科学基金(S2013010013637);广州市重点医学学科建设项目
作者单位E-mail
李晓宁 广东药学院公共卫生学院广东省分子流行病学重点实验室, 广州 510310  
罗雷 广州市疾病预防控制中心  
肖新才 广州市疾病预防控制中心  
景钦隆 广州市疾病预防控制中心  
魏跃红 广州市疾病预防控制中心  
李意兰 广州市疾病预防控制中心  
曹庆 广州市疾病预防控制中心  
杨智聪 广州市疾病预防控制中心 yangzc@gzcdc.org.cn 
许雅 广东药学院公共卫生学院广东省分子流行病学重点实验室, 广州 510310 yaoxuya@163.com 
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中文摘要:
      目的 了解广州市登革热散发和暴发蚊媒密度指标布雷图指数(BI)的临界值。方法 以广州市为研究区域, 对2006-2012 年国家传染病监测与管理系统中广州市登革热病例进行描述性分析, 采用受试者工作特征(ROC)曲线判断登革热在街道内散发与暴发BI 的临界值。结果 2006-2012 年广州市共报告本地病例1 038 例, 共有71 次登革热暴发, 259 次散发。ROC曲线分析显示, BI 值为6.4 时预测散发的约登指数最高(1.469), 灵敏度为67.8%, 特异度为79.1%;BI 为9.5 时预测暴发的约登指数最高(1.726), 灵敏度为81.7%, 特异度为90.9%。结论 预测登革热散发和暴发的BI 临界值分别可定为5.0 和9.5, 实际工作中, 应根据监测目的和人力物力对临界值进行调整, 以得到更为合理的灵敏度和特异度。
英文摘要:
      Objective To understand the threshold of Breteau Index(BI)on Dengue fever outbreak in Guangzhou. Methods Dengue cases from Guangzhou during 2006 to 2012 in the National Infectious Disease Report and Management System were collected and described. Receiveroperating characteristic (ROC)curve was used to judge the threshold of BI on the outbreaks of Dengue fever. Results A total of 1 038 local cases were reported from 2006 to 2012 in Guangzhou city, with a total of 71 outbreaks and 259 sporadic episodes. Data from the ROC curve analysis showed that the highest Youden index that BI predicting Dengue fever outbreaks or sporadic were 6.4 and 9.5, respectively. When using BI=6.4 in predicting the sporadic case of Dengue, sensitivity and specificity were 67.8% , 79.1% , respectively. When using BI=9.5 in predicting the outbreaks of Dengue, sensitivity and specificity were 81.7%, 90.9%, respectively. Conclusion Both BI=5.0 and BI=9.5 showed effects on predicting the nature of sporadic or outbreak on Dengue, suggesting that the threshold need to be monitored, according to the purpose of control and availability of manpower, in order to get better sensitivity and specificity.
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