文章摘要
周静雯,吴佳慧,梁柱,佟斯琴,佟伟军,张永红,张绍艳.内蒙古部分地区蒙古族空腹血糖受损人群10年转归及影响因素分析[J].中华流行病学杂志,2014,35(11):1241-1243
内蒙古部分地区蒙古族空腹血糖受损人群10年转归及影响因素分析
Outcomes and correlated factors in patients with impaired fasting glucose: a ten-year follow-up analysis
投稿时间:2014-05-19  
DOI:10.3760/cma.j.issn.0254-6450.2014.11.014
中文关键词: 空腹血糖受损;糖尿病;影响因素;转归
英文关键词: Impaired fasting glucose;Diabetes mellitus;Influence factors;Outcome
基金项目:国家自然科学基金(81102190)
作者单位E-mail
周静雯 215123 苏州大学医学部公共卫生学院流行病学教研室  
吴佳慧 215123 苏州大学医学部公共卫生学院流行病学教研室  
梁柱 215123 苏州大学医学部公共卫生学院流行病学教研室  
佟斯琴 内蒙古通辽市奈曼旗固日班花苏木卫生院  
佟伟军 215123 苏州大学医学部公共卫生学院流行病学教研室  
张永红 215123 苏州大学医学部公共卫生学院流行病学教研室  
张绍艳 215123 苏州大学医学部公共卫生学院流行病学教研室 zhangsy@suda.edu.cn 
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中文摘要:
      目的 分析蒙古族人群中IFG患者10年的转归情况及其影响因素。方法 于2002-2003年对内蒙古科左后旗和奈曼旗的32个行政村>20岁居民进行基线调查,选择IFG且无糖尿病史的人群作为研究对象,于2013年开展随访。采用多分类logistic回归进行统计学分析。结果 384人中,150人(39.1%)FPG恢复正常,174人(45.3%)为IFG,60人(15.6%)进展为糖尿病。经多因素调整后,TG升高是IFG人群恢复为正常的抑制因素(OR=0.692,95%CI:0.502~0.952),差异有统计学意义(P<0.05);年龄增加和腹型肥胖是IFG人群进展为糖尿病的危险因素(OR=1.052,95%CI:1.014~1.090;OR=2.924,95%CI:1.353~6.320),差异均有统计学意义(均P<0.05)。结论 蒙古族IFG人群中15.6%进展为糖尿病;TG水平的升高在IFG人群恢复正常的过程中起到抑制作用,而年龄和腹型肥胖是IFG人群进展为糖尿病的危险因素。
英文摘要:
      Objective To investigate the outcomes and relative risk factors in subjects with impaired fasting glucose in Inner Mongolia,China. Method A total number of 32 villages in Kezuohou Banner and Naiman areas in Inner Mongolia were selected as the baseline surveys study fields from 2002 to 2003. Patients with IFG(5.6 mmol/L≤FPG<7.0 mmol/L) but without history of diabetes were selected as the study subjects. A follow-up study was conducted in 2013. Multinomial logistic regression analysis was used to evaluate the correlated factors. Results There were 384 patients with IFG recruited in the study. Out of them,150(39.1%) progressed to normoglycaemia,174(45.3%) remained as IFG,and 60(15.6%) developed into type 2 diabetes mellitus. Through adjustment multivariately,patients that returning to the status of normoglycaemia were significantly associated under the function of TG (OR=0.692,95%CI:0.502-0.952,P<0.05) and those developed to diabetes were significantly associated with factors as age (OR=1.052,95%CI:1.014-1.090,P<0.05) or obesity (OR=2.924,95%CI:1.353-6.320,P<0.05). Conclusion 15.6% of the IFG patients developed diabetes mellitus among the Inner Mongolian population. Elevated TG was an inhibition factor for patients returning to normoglycaemia while both age and abdominal obesity were risk factors for the development of diabetes in the Inner Mongolian population.
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