文章摘要
潘晓红,蒋均,何欢,陈琳,杨介者,张洪波,汪宁.浙江省2011年新型毒品使用者艾滋病、梅毒和丙型肝炎感染状况及其危险行为特征分析[J].中华流行病学杂志,2015,36(9):934-940
浙江省2011年新型毒品使用者艾滋病、梅毒和丙型肝炎感染状况及其危险行为特征分析
Survey of prevalence of HIV infection,syphilis and HCV infection and related risk behaviors among club drug users in Zhejiang,2011
收稿日期:2015-02-25  出版日期:2015-09-10
DOI:10.3760/cma.j.issn.0254-6450.2015.09.006
中文关键词: 新型毒品使用者;艾滋病;梅毒;丙型肝炎;危险性行为
英文关键词: Club drug users;AIDS;Syphilis;HCV;High risk sex behaviors
基金项目:国家科技重大专项(2012ZX10001-001)
作者单位E-mail
潘晓红 310051 杭州, 浙江省疾病预防控制中心 xhpan@cdc.zj.cn 
蒋均 310051 杭州, 浙江省疾病预防控制中心  
何欢 安徽医科大学公共卫生学院流行病与卫生统计学系  
陈琳 310051 杭州, 浙江省疾病预防控制中心  
杨介者 310051 杭州, 浙江省疾病预防控制中心  
张洪波 安徽医科大学公共卫生学院流行病与卫生统计学系  
汪宁 中国疾病预防控制中心性病艾滋病预防控制中心  
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中文摘要:
      目的 了解浙江省新型毒品使用者艾滋病、梅毒和丙型肝炎(丙肝)感染水平、相关行为特征以及相互关系。方法 2011年在浙江省6个城市对戒毒人员进行匿名问卷调查,调查内容包括社会人口学、使用毒品种类、性行为、接受干预情况,并采集血液进行艾滋病、梅毒和丙肝抗体检测。利用SPSS 15.0统计软件进行数据分析。结果 共调查3 253人,其中新型毒品使用者1 298人,占39.9%,北部和中部地区、女性、≤25岁年龄组、浙江省户籍和有商业性性行为的吸毒者中使用新型毒品的比例较高。1 298例新型毒品使用者中,使用冰毒者占91.2%,HIV抗体阳性率为0.1%(95%CI:0.0%~0.2%),梅毒抗体阳性率为8.1%(95%CI:6.6%~9.6%),丙肝抗体阳性率为17.3%(95%CI:15.2%~19.4%);艾滋病知识知晓率为12.7%,有注射吸毒史者占9.2%,最近一年有商业性性行为者占29.6%。曾接受安全套发放和咨询的比例为33.4%,曾接受艾滋病检测的比例为14.0%。多因素分析表明,来自中部和南部地区的新型毒品使用者的梅毒感染、丙肝感染和有注射吸毒行为比例高于来自北部地区者;女性是梅毒感染的相关因素;曾注射吸毒和最近一年有商业性性行为与丙肝感染相互关联;曾注射吸毒行为与最近一年商业性性行为相互关联。男性、浙江省户籍及未接受过安全套发放和咨询者更有可能发生商业性性行为。结论 新型毒品使用者梅毒和丙肝感染水平高,不安全行为发生率高,接受干预服务比例低,提示需要提高对该人群的艾滋病、梅毒和丙肝感染风险的认识,设计制定针对该人群的有效干预措施,扩大干预覆盖率。
英文摘要:
      Objective To understand the prevalence of HIV infection,syphilis and hepatitis C infection and related risk behaviors among club drug users in Zhejiang province. Methods The drug users were interviewed with questionnaires in 2011 to collect the information about their demographic characteristics,sexual behaviors,drug use behaviors and the utilization of intervention services. Blood samples were collected from them to detect HIV,syphilis and HCV antibodies. Results A total of 3 253 drug users were surveyed,in which 1 298 were club drug users,accounted for 39.9%. The proportion of club drug users was high in northern and central Zhejiang,in females,in age group ≤25 years,in local residents and in those having commercial sexual behaviors during previous 12 months. Of the 1 298 club drug users,91.2% were methamphetamine users,0.1% were infected with HIV(95%CI:0.0%-0.2%),8.1% suffered from syphilis(95%CI:6.6%-9.6%),17.3% were infected with HCV(95%CI:15.2%-19.4%). Among the interviewed club drug users,12.7% were aware of AIDS,9.2% had injecting drug use histories,29.6% reported having commercial sex during the previous 12 months,only 33.4% received free condom and counsel,14.0% received HIV test. Multivariate logistic regression analysis indicated that living in central and southern Zhejiang was associated with syphilis prevalence,HCV infection and injecting drug use behavior,being female was associated with syphilis prevalence. Injecting drug use and commercial sex during the previous 12 months were associated with HCV infection,and injecting drug use and commercial sex during the previous 12 months were associated with each other. Among the 1 285 club drug users,males,local residents in Zhejiang and those who never received free condom or counsel were more likely to have commercial sex. Conclusion The prevalence of syphilis and HCV infection are high and unprotected sexual behaviors are common among the club drug users in Zhejiang,but less intervention services were received by them,suggesting that more attention should be paid to the prevention and control of HIV,HCV infections and syphilis in club drug users by taking effective intervention measures and increasing intervention coverage.
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