| 聂珺妍,喻红辉,王智强,汪蕾蕾,韩娟,王友洁,杜玉开,沈敏.儿童期不良经历与成年后慢性病的相关性研究[J].中华流行病学杂志,2015,36(9):953-957 |
| 儿童期不良经历与成年后慢性病的相关性研究 |
| Association between adverse experiences in childhood and risk of chronic diseases in adulthood |
| 收稿日期:2015-01-30 出版日期:2015-09-10 |
| DOI：10.3760/cma.j.issn.0254-6450.2015.09.010 |
| 中文关键词: 儿童期不良经历 慢性病 成年人 相关性 |
| 英文关键词: Adverse childhood experiences Chronic disease Adult Relevance |
| 基金项目:湖北省自然科学基金(2013CFB125) |
| 作者 | 单位 | E-mail | | 聂珺妍 | 430030 武汉, 华中科技大学同济医学院公共卫生学院儿少卫生与妇幼保健学系
1. 430030 武汉, 华中科技大学同济医学院公共卫生学院儿少卫生与妇幼保健学系 | | | 喻红辉 | 430030 武汉, 华中科技大学同济医学院附属同济医院麻醉科1. 430030 武汉, 华中科技大学同济医学院公共卫生学院儿少卫生与妇幼保健学系 | | | 王智强 | 430030 武汉, 华中科技大学同济医学院公共卫生学院儿少卫生与妇幼保健学系
1. 430030 武汉, 华中科技大学同济医学院公共卫生学院儿少卫生与妇幼保健学系 | | | 汪蕾蕾 | 430030 武汉, 华中科技大学同济医学院公共卫生学院儿少卫生与妇幼保健学系
1. 430030 武汉, 华中科技大学同济医学院公共卫生学院儿少卫生与妇幼保健学系 | | | 韩娟 | 430030 武汉, 华中科技大学同济医学院公共卫生学院儿少卫生与妇幼保健学系
1. 430030 武汉, 华中科技大学同济医学院公共卫生学院儿少卫生与妇幼保健学系 | | | 王友洁 | 430030 武汉, 华中科技大学同济医学院公共卫生学院儿少卫生与妇幼保健学系
1. 430030 武汉, 华中科技大学同济医学院公共卫生学院儿少卫生与妇幼保健学系 | | | 杜玉开 | 430030 武汉, 华中科技大学同济医学院公共卫生学院儿少卫生与妇幼保健学系
1. 430030 武汉, 华中科技大学同济医学院公共卫生学院儿少卫生与妇幼保健学系 | | | 沈敏 | 430030 武汉, 华中科技大学同济医学院公共卫生学院儿少卫生与妇幼保健学系 | shenmin@mail.hust.edu.cn |
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| 中文摘要: |
| 目的 了解18～59岁成年人儿童期不良经历的流行特征,探讨与成年后慢性病发病的相关性,为慢性病早期预防提供依据。方法 采用横断面研究,在湖北省麻城市龙池、南湖和鼓楼3个街道随机整群抽取18～59岁成年人,回顾性调查儿童期不良经历与成年后的慢性病患病情况,采用单因素和多因素logistic回归分析相关性。结果 共调查1 767名18～59岁成年人,其中1 501份问卷有效。男女性平均年龄分别为(36.32±10.20)岁和(35.72±9.08)岁。儿童期不良经历的发生率为66.22%,包括情感忽视(26.65%)、身体虐待(21.52%)、父母分居/离异(21.45%)、受到欺负(3.33%)、家庭物质滥用(1.53%)等。儿童期不良经历可增加成年后的慢性病发病风险,随着儿童期不良经历评分的增加,慢性病发病风险有增加趋势(Z=-5.902 1,P< 0.000 1)。多因素分析显示,家庭物质滥用(OR=2.82,95%CI:1.16～6.80)、受到欺负(OR=2.59,95%CI:1.39～4.80)、躯体虐待(OR=1.93,95%CI:1.41～2.64)和父母分居/离异(OR=1.51,95%CI:1.09～2.09)增加成年后慢性病发病风险。结论 儿童期不良经历发生率较高,可增加成年后慢性病发病风险,慢性病的早期预防应从儿童期开始。 |
| 英文摘要: |
| Objective To analyze the prevalence and characteristics of childhood adverse experiences among adults aged 18-59 years and understand the association between childhood adverse experiences and risk of chronic diseases in adulthood. Methods A cross-sectional study was conducted with a questionnaire among adults aged 18-59 years selected through cluster random sampling from 3 communities in Macheng,Hubei province. Uinivariate and multivariate logistic regression analyses were conducted to evaluate the association between adverse experiences in childhood and the risk of chronic diseases in adulthood. Results A total of 1 767 adults aged 18-59 years were surveyed and 1 501 valid questionnaires were returned. The average age was (36.32±10.20) years for males and (35.72±9.08) years for females. The prevalence rate of childhood adverse experiences was 66.22%. The risk of chronic disease in adults increased with the increase of the score indicating childhood adverse experiences (Z=-5.902 1,P< 0.000 1). Multivariate logistic regression analysis showed that being physically abused (OR=1.93,95%CI:1.41-2.64),substance abuse in family (OR=2.82,95%CI:1.16-6.80),being bullied (OR=2.59,95%CI:1.39-4.80) and parents separation/divorce (OR=1.51,95%CI:1.09-2.09) were significantly associated with risk of chronic diseases in adulthood. Conclusion The prevalence of adverse childhood experiences was high in adults aged 18-59 years,which was significantly associated with the risk of chronic diseases in adulthood. Early prevention of chronic diseases should be conducted in childhood. |
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