| 胡晓斌,白亚娜,蒲宏全,张凯,程宁,李海燕,申希平,李富秀,任晓卫,朱锦兵,郑山,王敏珍,代敏.金昌队列人群肝癌疾病负担研究[J].中华流行病学杂志,2016,37(3):321-324 |
| 金昌队列人群肝癌疾病负担研究 |
| Disease burden of liver cancer in Jinchang cohort |
| 收稿日期:2015-10-28 出版日期:2016-03-15 |
| DOI：10.3760/cma.j.issn.0254-6450.2016.03.005 |
| 中文关键词: 肝癌 队列 死亡率 疾病负担 趋势 |
| 英文关键词: Liver cancer Cohort Mortality rate Disease burden Trends |
| 基金项目:国家重大公共卫生服务项目(财社2012-64);金川集团股份有限公司科学技术项目(JKZ20120013) |
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| 中文摘要: |
| 目的 揭示金昌队列人群肝癌疾病负担现状及其变化趋势。方法 收集金昌队列人群2001－2013年死亡人群中肝癌资料及2001－2010年肝癌住院患者资料,应用死亡率、标化死亡率、直接经济负担、潜在减寿年(PYLL)、人均PYLL(APYLL)、潜在工作损失年(WPYLL)以及人均WPYLL(AWPYLL)等指标分析肝癌疾病负担,运用Spearman秩相关、平均增长速度等描述疾病负担变化趋势。结果 2001－2013年金昌队列人群因肝癌死亡207人,占全部癌症死亡人数的16.68%;2001－2010年金昌队列人群肝癌住院患者259例,占全部癌症住院患者的6.79%,死亡83例,病死率为32.05%。肝癌死亡以男性为主,占88.89%,标化死亡率为42.32/10万;女性占11.11%,标化死亡率为15.31/10万;连续13年队列人群肝癌死亡率、男性肝癌死亡率随年份呈增长趋势,增长速度分别为5.62%、5.16%。肝癌死亡以60~69岁、50~59岁为主,分别占26.57%、24.15%。肝癌造成队列人群PYLL与APYLL分别为2 906.76人年和14.0年,WPYLL与AWPYLL分别为1 477.00人年和7.14年,男女性AWYPLL相当。肝癌住院患者例均直接经济负担为6 270.78元,日均直接经济负担为301.75元,例均住院天数为21.32。结论 金昌队列人群10余年来肝癌死亡率呈上升趋势,疾病负担持续沉重。 |
| 英文摘要: |
| Objective To understand the current status of the disease burden of liver cancer in Jinchang cohort. Methods All the liver cancer death data from 2001 to 2013 and medical records of liver cancer cases from 2001 to 2010 in Jinchang cohort were collected for the analyses of the mortality, standardized mortality, potential years of life lost (PYLL) and working PYLL (WPYLL) associated with liver cancer. Spearman correlation and the average growth rate were used to analyze the trends. Results A total of 207 liver cancer deaths occurred in Jinchang cohort from 2001 to 2013, accounting for 16.68% of total cancer deaths. There were 259 liver cancer inpatients, accounting for 6.79% of the total cancer cases inpatients, in which 83 died (32.05%). Liver cancer death mainly occurred in males, accounting for 88.89%, and the liver cancer deaths in females accounted for 11.11%. The standardized mortality rate was 42.32/100 000 in males and 15.31/100 000 in females. The growth rate of liver cancer mortality was 5.62% from 2001 to 2013. Liver cancer deaths mainly occurred in age groups 60-69 years (26.57%) and 50-59 years (24.15%). The PYLL was 2 906.76 person-years, the average PYLL was 14.04 years. The WPYLL was 1 477.00 person-years and the average WPYLL was 7.14 years. The direct economic burden of liver cancer was 6 270.78 Yuan per person, 301.75 Yuan per day. The average stay of hospitalization was 21.32 days. Conclusion The mortality rate of liver cancer is increasing and the disease burden is still heavy. |
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