文章摘要
董选军,孙继民,楼莲青,朱志宏,朱列波,楼挺.中国大陆第三例输入性寨卡病毒病病例调查分析[J].中华流行病学杂志,2016,37(5):597-599
中国大陆第三例输入性寨卡病毒病病例调查分析
Survey of the third Zika virus disease case in the mainland of China
收稿日期:2016-02-25  出版日期:2016-05-13
DOI:10.3760/cma.j.issn.0254-6450.2016.05.002
中文关键词: 寨卡病毒  流行病学调查
英文关键词: Zika virus  Epidemiological investigation
基金项目:
作者单位E-mail
董选军 322000 义乌市疾病预防控制中心  
孙继民 310051 杭州, 浙江省疾病预防控制中心传染病防制所  
楼莲青 322000 义乌市中心医院感染科 27384434@qq.com 
朱志宏 322000 义乌市疾病预防控制中心  
朱列波 322000 义乌市疾病预防控制中心  
楼挺 322000 义乌市疾病预防控制中心  
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中文摘要:
      目的 对中国大陆第三例输入性寨卡病毒病病例进行调查分析,为防控寨卡病毒病提供工作经验和参考依据。方法 对中国大陆第三例输入性寨卡病毒病病例的临床表现、实验室检测、诊疗和流行病学调查进行描述性分析。结果 2016年2月19日,经中国CDC有关专家复核和专家会诊,我国义乌市确诊1例从斐济、萨摩亚旅游归来的输入性寨卡病毒病病例,病例曾在萨摩亚有蚊虫叮咬史。病例2月14日发病,15日出疹,16日出现结膜炎,16日收住入院,17日体温正常,19日皮疹消失,20日结膜炎消失。血液中寨卡病毒核酸检测阳性持续仅3 d,血液核酸检测阴性4 d后尿液仍可检测到核酸阳性。结论 该病例寨卡病毒病症状典型,早期可采集病例血液进行寨卡病毒核酸检测,体温正常后应采集尿液进行寨卡病毒核酸检测。
英文摘要:
      Objective To evaluate the performance of Zika virus (ZIKV) disease prevention and control. Methods Descriptive epidemiological analysis was conducted on the clinical manifestations, laboratory detection results and disease progression of the third imported ZIKV disease case in the mainland of China. Results On 19 February 2016, a ZIKV disease case was confirmed in Yiwu, Zhejiang province, which was the third imported case of ZIKV disease confirmed by China CDC laboratory and expert consulting. The patient just had a travel to Fiji and Samoa and had mosquito bite history in Samoa. The patient was hospitalized on 16 February after the onset on 14 February and the eruption on 15 February. The body temperature of the patient became normal on 17 February, the rash disappeared on 19 February and the conjunctivitis resolved on 20 February. The positive detection of the viral nucleic acid in blood was only for 3 consecutive days, and the viral nucleic acid could be detected in urine even after negative detection in blood for 4 days. Conclusion The symptoms of the patient were typical. ZIKV can be detected by using blood sample in early phase, but after body temperature become normal, the virus can be detected in urine.
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