文章摘要
王富珍,郑徽,刘建华,孙校金,缪宁,沈立萍,张国民,崔富强.中国2014年2~29岁人群甲型肝炎疫苗接种率及甲型肝炎报告发病分析[J].中华流行病学杂志,2016,37(8):1099-1104
中国2014年2~29岁人群甲型肝炎疫苗接种率及甲型肝炎报告发病分析
The coverage of hepatitis A vaccine among 2-29 year olds and the reporting incidence of hepatitis A in China, 2014
收稿日期:2016-03-29  出版日期:2016-08-10
DOI:10.3760/cma.j.issn.0254-6450.2016.08.009
中文关键词: 甲型肝炎;甲型肝炎疫苗;接种率;发病率
英文关键词: Hepatitis A;Hepatitis A vaccine;Vaccination rate;Incidence rate
基金项目:国家科技重大专项(2012ZX10002001)
作者单位E-mail
王富珍 100050 北京, 中国疾病预防控制中心免疫规划中心流行病学二室  
郑徽 100050 北京, 中国疾病预防控制中心免疫规划中心流行病学二室  
刘建华 510440 广州市疾病预防控制中心免疫规划科  
孙校金 100050 北京, 中国疾病预防控制中心免疫规划中心流行病学二室  
缪宁 100050 北京, 中国疾病预防控制中心免疫规划中心流行病学二室  
沈立萍 102206 北京, 中国疾病预防控制中心病毒病预防控制所肝炎室  
张国民 100050 北京, 中国疾病预防控制中心免疫规划中心流行病学二室  
崔富强 100050 北京, 中国疾病预防控制中心免疫规划中心 cuifuq@126.com 
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中文摘要:
      目的 评价中国2~29岁人群甲型肝炎(甲肝)疫苗接种率和甲肝报告发病率。方法 基于2014年全国乙型肝炎血清流行病学调查数据库中甲肝疫苗接种史信息,运用SAS 9.4软件分析2~29岁人群甲肝疫苗接种率。通过全国传染病报告信息管理系统获取2004-2014年甲肝报告发病资料,运用Excel 2007软件分析甲肝报告发病率。结果 共分析全国2~29岁人群29 058人,甲肝疫苗接种率为44.6%,年龄越小,甲肝疫苗接种率越高,其中2~6岁、7~14岁人群甲肝疫苗接种率分别为91.2%、76.0%。2004-2014年全国甲肝报告发病率逐年下降,其中2~6岁、7~14岁人群和全人群2007-2013年甲肝报告发病率下降幅度分别为82.5%、90.6%、72.1%。结论 甲肝疫苗纳入我国扩大免疫规划以后,2~6岁出生人群甲肝疫苗接种率达到90%以上,无城乡差异;2~6岁甲肝报告发病率下降幅度大于全人群。
英文摘要:
      Objective To evaluate the hepatitis A vaccine coverage among 2-29 year olds and the reported incidence rates of hepatitis A, in China. Methods Based on data from the national sero-survey on hepatitis B in 2014, information on hepatitis A vaccine immunization was collected and the coverage of hepatitis A vaccine was analyzed with SAS software (Version 9.4). Incidence data on hepatitis A was also collected from the National Notifiable Disease Reporting System between 2004 and 2014, and analyzed using the micro-software Excel 2007. Results Totally, data involving 29 058 people aged 2-29 years were available for analysis and the overall hepatitis A vaccine coverage was 44.6%. The younger the age, the higher the coverage appeared. Among the 2-6 year and the 7-14 year olds, rates of hepatitis A vaccine coverage were 91.2% and 76.0% respectively. From 2004 to 2014, the incidence rates of hepatitis A in the whole population were declining, annually. The incidence rates showed continuously declining as 82.5%, 90.6%, 72.1% among children at the age groups of 2-6 years, 7-14 years and in the whole population, from 2007 to 2013. Conclusion After the inclusion of hepatitis A vaccine into the Expanded Programe on Immunization (EPI), the coverage of hepatitis A vaccine among the 2-6 year olds increased to over 90%, with no obvious difference between the urban and rural areas. Incidence of hepatitis A in the 2-6 year olds showed a more rapid decline than that in the whole population.
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