文章摘要
吴含,曹明昆,杨丽萍,姜宝法.足月低出生体重儿危险因素的Meta分析[J].中华流行病学杂志,2016,37(10):1417-1423
足月低出生体重儿危险因素的Meta分析
Meta-analysis on partial risk factors of full-term infants with low birth weight
收稿日期:2016-04-12  出版日期:2016-10-13
DOI:10.3760/cma.j.issn.0254-6450.2016.10.020
中文关键词: 低出生体重;足月;危险因素; Meta分析
英文关键词: Low birth weight;Full-term;Risk factors;Meta-analysis
基金项目:山东省自然科学基金(ZR2015HM076)
作者单位E-mail
吴含 250012 济南, 山东大学公共卫生学院流行病学系  
曹明昆 250012 济南, 山东大学公共卫生学院流行病学系  
杨丽萍 250012 济南, 山东大学公共卫生学院流行病学系  
姜宝法 250012 济南, 山东大学公共卫生学院流行病学系 bjiang@sdu.edu.cn 
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中文摘要:
      目的 综合评价足月低出生体重儿的危险因素。方法 检索中文数据库(中国生物医学文献数据库、中国期刊全文数据库、数字化期刊全文数据库)、英文数据库(Medline、Embase)中1980年至2016年2月25日期间公开发表的相关文献,并按照事先确定的纳入与排除标准剔除不符合要求的文献,对纳入文献采用Stata 13.0软件进行Meta分析。结果 共纳入23篇文献,包含278 020例研究对象。胎儿性别为女(合并OR=1.60,95% CI:1.49~1.72)、产前检查次数较少(合并OR=1.81,95% CI:1.54~2.11)、母亲被动吸烟(合并OR=1.49,95% CI:1.08~2.06)、妊娠期高血压(合并OR=2.96,95% CI:1.85~4.74)、羊水过少(合并OR=2.71,95% CI:1.87~3.93)是足月低出生体重儿的危险因素。结论 针对足月低出生体重儿的危险因素,应鼓励孕妇产前检查,及时发现并诊治孕妇妊娠期合并症,并通过相关宣教促使孕妇主动避免被动吸烟,从而提升新生儿出生质量。
英文摘要:
      Objective To evaluate the risk factors of full-term infants with low birth weight. Methods All related Chinese and English literatures published from 1980 to February 25, 2016 were collected from CBM, CNKI, Wang Fang Data, Medline and Embase databases, and screened with inclusion and exclusion criteria and Stata13.0 software was used in this Meta-analysis. Results Twenty three studies were included and there were 278 020 subjects. Female infants (pooled OR=1.60, 95%CI:1.49-1.72), less antenatal care visits (pooled OR=1.81, 95%CI:1.54-2.11), maternal passive smoking (pooled OR=1.49, 95%CI:1.08-2.06), pregnancy-induced hypertension (pooled OR=2.96, 95%CI:1.85-4.74) and hypamnion (pooled OR=2.71, 95%CI:1.87-3.93) were the risk factors for full-term infants with low birth weight. Conclusion Departments of maternal and health care should encourage pregnant women to have antenatal care visits to find and treat their pregnancy complications, and avoid passive smoking actively through health education for the purpose to prompt the birth quality of infants.
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