| 王玲玲,柏如海,章琦,颜虹.西安市2010-2013年大气污染对育龄妇女妊娠结局的影响[J].中华流行病学杂志,2016,37(11):1473-1475 |
| 西安市2010-2013年大气污染对育龄妇女妊娠结局的影响 |
| Effect of air pollution on pregnancy outcome of women at reproductive age in Xi'an, 2010-2013 |
| 收稿日期:2016-07-07 出版日期:2016-11-10 |
| DOI：10.3760/cma.j.issn.0254-6450.2016.11.008 |
| 中文关键词: 大气污染 育龄妇女 妊娠结局 |
| 英文关键词: Air pollution Reproductive women Pregnancy outcome |
| 基金项目:国家自然科学基金（81230016） |
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| 摘要点击次数: 2864 |
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| 中文摘要: |
| 目的 了解西安市不同大气污染程度地区不良妊娠结局的发生现况。方法 选取西安市主城区和城乡结合区作为研究地点，采用分层多阶段随机抽样方法，以问卷调查方式收集2010-2013年怀孕且怀孕结局明确的育龄妇女妊娠相关信息。结果 西安市主城区SO2年平均浓度（38～54 μg/m3）高于城乡结合区（29～43 μg/m3），NO2年平均浓度（29～87 μg/m3）高于城乡结合区（22～42 μg/m3）；主城区的出生缺陷发生率（2.1%）高于城乡结合区（1.0%），差异有统计学意义（P<0.05）。运用logistic回归模型控制混杂因素后，主城区出生缺陷发生的危险性仍高于城乡结合区，差异有统计学意义（P<0.05）。其他不良妊娠结局的发生在主城区和城乡结合区之间的差异无统计学意义。结论 大气污染与不良妊娠结局有关。 |
| 英文摘要: |
| Objective To compare the differences in the incidence of adverse pregnancy outcome in different area, and confirm if the incidence of adverse pregnancy outcomes is closely associated with air pollution. Methods A cross-sectional study was conducted in the central urban area and the rural-urban area of Xi'an through a questionnaire survey conducted among the local reproductive women selected through multistage stratified random sampling during 2010-2013, all the reproductive women surveyed were in pregnancy or had definite pregnancy outcomes. Results The annual average of SO2 concentration in the central urban area was 38-54 μg/m3, higher than that in the rural-urban area (29-43 μg/m3). The annual average NO2 concentration in the central urban area was 29-87 μg/m3, higher than that in the rural-urban area (22-42 μg/m3). The incidence of birth defects was higher in the central urban area than in the rural-urban area (2.1% vs. 1.0%), the difference was significant (P<0.05). After adjusting for confounding factors, logistic regression analysis showed the incidence of birth defects in the central urban area was still significantly higher than that in the rural-urban area, the difference was significant (P<0.05). Conclusion The incidence of adverse pregnancy was closely associated with the level of air pollution. |
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