文章摘要
王波,李立明.科学看待精准医学的研究与进展[J].中华流行病学杂志,2017,38(1):1-2
科学看待精准医学的研究与进展
Progress in precision medicine: a scientific perspective
收稿日期:2016-11-28  出版日期:2017-01-12
DOI:10.3760/cma.j.issn.0254-6450.2017.01.001
中文关键词: 精准医学;基因组学;个体化医学;精准预防
英文关键词: Precision medicine;Genomics;Personalized medicine;Precision prevention
基金项目:
作者单位E-mail
王波 100730 北京, 中国医学科学院健康科普研究中心  
李立明 100191 北京大学公共卫生学院流行病与卫生统计学系 lmlee@vip.163.com 
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中文摘要:
      精准医学是一种将个体基因、环境与生活习惯差异考虑在内的疾病预防与治疗的新策略,旨在对疾病进行精确分类及诊断,为患者提供个性化、更具针对性的预防和治疗措施。大规模人群队列研究是精准医学研究的重要基础,能够为精准医学实践提供循证医学的最佳证据。对精准医学的批评与质疑主要集中在受益人群少、对健康社会决定因素的忽视以及可能导致有限医疗资源的浪费。尽管这样,精准医学仍然是一个“希望无限的领域”,并有望成为未来医疗保健的实践模式。
英文摘要:
      Precision medicine is a new strategy for disease prevention and treatment by taking into account differences in genetics, environment and lifestyles among individuals and making precise diseases classification and diagnosis, which can provide patients with personalized, targeted prevention and treatment. Large-scale population cohort studies are fundamental for precision medicine research, and could produce best evidence for precision medicine practices. Current criticisms on precision medicine mainly focus on the very small proportion of benefited patients, the neglect of social determinants for health, and the possible waste of limited medical resources. In spite of this, precision medicine is still a most hopeful research area, and would become a health care practice model in the future.
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