文章摘要
柳忠泉,周宁,柏建芸,郭燕,于茂河.天津市2004-2014年HIV/AIDS生存时间及影响因素[J].中华流行病学杂志,2017,38(3):369-373
天津市2004-2014年HIV/AIDS生存时间及影响因素
Analysis of survival and influencing factors of HIV/AIDS patients in Tianjin, 2004-2014
投稿时间:2016-09-21  
DOI:10.3760/cma.j.issn.0254-6450.2017.03.019
中文关键词: 艾滋病病毒感染者/艾滋病患者;生存时间;影响因素
英文关键词: HIV/AIDS;Survival time;Influencing factor
基金项目:
作者单位E-mail
柳忠泉 300011 天津市疾病预防控制中心性病艾滋病预防控制室 275426637@qq.com 
周宁 300011 天津市疾病预防控制中心性病艾滋病预防控制室  
柏建芸 300011 天津市疾病预防控制中心性病艾滋病预防控制室  
郭燕 300011 天津市疾病预防控制中心性病艾滋病预防控制室  
于茂河 300011 天津市疾病预防控制中心性病艾滋病预防控制室  
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中文摘要:
      目的 了解天津市HIV/AIDS生存时间及影响因素。方法 统计2004-2014年全国艾滋病防治信息系统中天津市报告的全部HIV/AIDS,运用寿命表法和Kaplan-Meier方法计算生存时间及各年生存率,运用单因素及多因素Cox回归方法对生存时间的影响因素进行相关分析。结果 2 775例HIV/AIDS病例1年、3年、5年、10年、11年累计生存率分别为91%、88%、86%、79%和79%;AIDS患者的死亡风险高于HIV感染者(χ2=107.622,P<0.001);多因素Cox比例风险回归分析发现,感染途径、病例来源、抗病毒治疗和首次CD4+T淋巴细胞(CD4)计数均是影响AIDS患者生存时间的因素。结论 早发现和早治疗能够明显降低HIV/AIDS的死亡风险,提高生存时间,应加强HIV/AIDS早发现和早治疗工作。
英文摘要:
      Objective To understand the survival and influencing factors of HIV/AIDS patients in Tianjin. Methods The data of HIV/AIDS cases reported in Tianjin during 2004-2014, which were collected from National AIDS Prevention and Control Information System, were analyzed by using life table and Kaplan Meier method to calculate survival time and the survival rate, and univariate and multivariate Cox regression analysis was conducted to identify the influencing factors for survival time. Results For the 2 775 HIV/AIDS patients, 1 year, 3 years, 5 years, 10 years and 11 years cumulative survival rates were 91%, 88%, 86%, 79% and 79% respectively. The risk of death in AIDS patients was higher than that in people living with HIV (χ2=107.622, P<0.001); Factors affecting the survival of people living with HIV were the first time CD4 value and antiviral treatment, and the influencing factors for survival of AIDS patients were the infection route, detection ways, first time CD4 value and antiviral treatment. Conclusion Early detection and early treatment can obviously reduce the risk for death of people living with HIV/AIDS. To improve the survival of HIV/AIDS patients, it is necessary to strengthen the early detection and early treatment of HIV infection.
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