| 朱鹏飞,张翼,班婕,李湉湉,施小明.中国空气污染与不良出生结局的研究进展[J].中华流行病学杂志,2017,38(3):393-399 |
| 中国空气污染与不良出生结局的研究进展 |
| Air pollution and adverse birth outcome in China: a comprehensive review |
| 收稿日期:2016-09-30 出版日期:2017-03-18 |
| DOI：10.3760/cma.j.issn.0254-6450.2017.03.024 |
| 中文关键词: 空气污染 婴儿 极低出生体重 早产 先天畸形 |
| 英文关键词: Air pollution Infant Very low birth weight Premature birth Congenital Abnormalities |
| 基金项目:国家自然科学基金（81573247） |
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| 中文摘要: |
| 目的 对中国空气污染与不良出生结局的相关研究进展进行综述。方法 通过检索万方、中国知网（CNKI）、PubMed、Science Direct、Web of Science等数据库2016年6月30日前发表的中国人群空气污染物暴露与不良出生结局相关文献，按照制定的纳入排除标准进行筛选，并对纳入的27篇文献进行综述。结果 中国孕产妇妊娠期间空气动力学直径≤10 μm的颗粒物（PM10）、二氧化硫（SO2）、二氧化氮（NO2）、总悬浮颗粒物（TSP）暴露可能增加低出生体重发病风险；妊娠期间暴露PM10、SO2、NO2可能增加早产发病风险；妊娠期间暴露SO2、NO2、臭氧（O3）、PM10可能增加先天性心脏缺陷及其他出生缺陷发病风险。结论 中国孕产妇妊娠期间空气污染物暴露可能增加不良出生结局发病风险，需进一步开展研究探讨其相关性。 |
| 英文摘要: |
| Objective To summarize the progress in the research of the association between air pollution and adverse birth outcomes in China. Methods A literature retrieval was conducted by using the databases of CNKI, Wanfang, Pubmed, Science Direct, and Web of Science to select relevant research papers published before 30th, June 2016 in China according to inclusion criteria. Finally, 27 papers were included in analysis. Results Exposure to particulate matter (PM10), sulfur dioxide (SO2), nitrogen dioxide (NO2), total suspended particles (TSP) during pregnancy might increase risk for low birth weight; exposure to PM10, SO2, NO2 during pregnancy might increase risk for premature birth; and exposure to SO2, NO2, ozone (O3), and PM10 during pregnancy might increase risk for congenital heart diseases and other birth defects. Conclusion Exposure to air pollutants during pregnancy might increase the risk for adverse birth outcomes, and further studies are needed to prove the association. |
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