文章摘要
杨静,刘韫宁,刘江美,曾新颖,赵艳芳,王卓群,周脉耕.2013年中国人群高胆固醇对期望寿命的影响[J].中华流行病学杂志,2017,38(8):1017-1021
2013年中国人群高胆固醇对期望寿命的影响
The effect of high total cholesterol on life expectancy in 2013 in China
收稿日期:2017-03-03  出版日期:2017-08-12
DOI:10.3760/cma.j.issn.0254-6450.2017.08.004
中文关键词: 胆固醇  人群归因分值  期望寿命
英文关键词: Cholesterol  Population attributable fraction  Life expectancy
基金项目:国家科技支撑计划(2013BAI04B02)
作者单位E-mail
杨静 100050 北京, 中国疾病预防控制中心慢性非传染性疾病预防控制中心科教与国际合作室  
刘韫宁 100050 北京, 中国疾病预防控制中心慢性非传染性疾病预防控制中心生命登记与死因监测室  
刘江美 100050 北京, 中国疾病预防控制中心慢性非传染性疾病预防控制中心生命登记与死因监测室  
曾新颖 100050 北京, 中国疾病预防控制中心慢性非传染性疾病预防控制中心综合防控与评价室  
赵艳芳 100050 北京, 中国疾病预防控制中心慢性非传染性疾病预防控制中心科教与国际合作室  
王卓群 100050 北京, 中国疾病预防控制中心慢性非传染性疾病预防控制中心科教与国际合作室  
周脉耕 100050 北京, 中国疾病预防控制中心慢性非传染性疾病预防控制中心 maigengzhou@126.com 
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中文摘要:
      目的 探讨中国人群高胆固醇对期望寿命的影响。方法 用2013年中国慢性病及其危险因素监测获得人群血清TC水平,计算分城乡、东中西部的高胆固醇人群归因分值,进而利用死因登记资料和人口统计数据,估算高胆固醇的归因死亡及其对期望寿命的影响。结果 2013年,中国≥ 25岁人群血清TC水平为(4.8±1.0)mmol/L,城市人群TC水平[(4.8±1.0)mmol/L]高于农村[(4.7±1.0)mmol/L],东部地区人群TC最高[(4.9±1.0)mmol/L],中部最低[(4.6±1.0)mmol/L],男性和女性TC均为(4.8±1.0)mmol/L。全部死亡中,2.9%归因于高胆固醇(264 998人),其中89.3%死于缺血性心脏病(236 540人),女性全死因人群归因分值(3.7%)高于男性(2.3%),城市(3.4%)高于农村(2.4%),东部最高(3.7%),西部最低(2.1%)。中国人群高胆固醇归因死亡率为19.6/10万,女性(21.2/10万)高于男性(18.0/10万),城市(20.8/10万)高于农村(18.2/10万),东部归因死亡率最高(23.2/10万),西部最低(15.6/10万)。2013年中国人群高胆固醇导致期望寿命损失为0.30岁,女性(0.35岁)高于男性(0.26岁);城市人群期望寿命损失(0.34岁)高于农村(0.28岁);东部人群期望寿命损失最高(0.36岁),西部最低(0.23岁)。结论 高胆固醇对中国人群期望寿命的影响存在性别、城乡和地区差异。女性、城市和东部受影响较大。
英文摘要:
      Objective To estimate the effect of high total cholesterol (TC) on life expectancy in China. Methods Population attributable fractions (PAF) of high TC were calculated in both urban,rural areas and regions, using data related to TC levels from the chronic disease risk factor surveillance in China, 2013. Together with PAFs, data related to death registry, demographics, attributable deaths from high TC and its effect on life expectancy, were estimated. Results In 2013, the TC level in Chinese population aged 25 and above appeared as (4.8±1.0) mmol/L, higher in urban areas[(4.8±1.0) mmol/L] than that in rural areas[(4.7±1.0) mmol/L)], with the highest in eastern regions[(4.9±1.0) mmol/L] and lowest in the central regions[(4.6±1.0) mmol/L]. TC level appeared as (4.8±1.0) mmol/L in both sexes. A total of 2.9% of all the deaths were attributed to high TC (264 998 deaths), among which 89.3% were caused by ischemic heart disease (236 540 deaths). PAF was seen higher in females (3.7%) than that in males (2.3%), higher in urban (3.4%) than that in rural areas (2.4%), with the highest in eastern (3.7%) and lowest in western regions (2.1%). Mortality that attributed to high TC was 19.6/100 000, higher in females (21.2/100 000) than that in males (18.0/100 000), higher in urban (20.8/100 000) than that in rural areas (18.2/100 000), with the highest in eastern (23.2/100 000) and lowest in western regions (15.6/100 000). In 2013, the loss of life expectancy that caused by high TC was 0.30 year, higher in females (0.35 year) than in males (0.26 year), higher in urban (0.34 year) than that in rural areas (0.28 year), with the highest seen in the eastern (0.36 year) and lowest (0.23 year) in the western regions. Conclusion In 2013, the effect of high TC on life expectancy appeared different between genders, urban and rural areas or regions, with greater impact on females, urban and eastern areas of the country.
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